Carvedilol 12.5 mg Tablet (Carvedilol)

Adult dose

Do not increase the dose or stop taking this medication without a physician’s instructions. 1. Essential hypertension 1) Adults (1) For the first 2 days, take 12.5 mg of carvedilol orally once daily, followed by 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is needed, increase to 25 mg twice daily. The maximum dose is 25 mg per dose and 50 mg per day. 2) Older adults In some older adults, 12.5 mg once daily may provide sufficient efficacy. However, if the effect is insufficient after 2 weeks of treatment, the dose may be increased. 2. Chronic stable angina 1) For the first 2 days, take 12.5 mg of this medication twice daily, followed by 25 mg twice daily. 2) The usual dose is 25 mg twice daily for 2 weeks. If a dose increase is needed (except in older adults), the dose may be increased to 50 mg twice daily. 3. Congestive heart failure Before starting treatment with this medication, the patient’s existing standard therapy (conventional treatment for chronic heart failure with an ACE inhibitor, a diuretic, and usually a digitalis preparation) must be stable. Fluid retention should also be minimized before starting treatment with this medication. 1) The usual initial dose is 3.125 mg of this medication twice daily for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg twice daily for 2 weeks, then to 12.5 mg twice daily for 2 weeks, and then to 25 mg twice daily. 2) Increase the dose gradually after taking each dose for at least 2 weeks, up to the dose the patient can tolerate. 3) The minimum effective dose is 6.25 mg twice daily. The maximum dose is 25 mg twice daily for patients weighing 85 kg or less, and 50 mg twice daily for patients weighing more than 85 kg. 4) To control the rate of absorption, it is recommended that this medication be taken with meals in the morning and evening. Taking it with meals slows the rate of absorption and may reduce the incidence of orthostatic hypotension.

This medication should not be used in certain patients. For example, it should not be administered to those who have had an allergic reaction to this medication or its components, patients in cardiogenic shock, patients with very slow heart rates or conduction issues, patients with cor pulmonale, patients with metabolic abnormalities due to diabetes, patients with severely impaired heart function, patients with respiratory diseases such as asthma or chronic obstructive pulmonary disease, pregnant or breastfeeding women, and patients with severe hypertension or liver dysfunction. It should be used cautiously in patients with diabetes, those sensitive to allergic reactions, patients with heart disease, patients with impaired kidney function, the elderly, and those with low blood pressure. Additionally, when taken with other medications, adverse reactions may occur due to interactions, so caution is necessary. While taking this medication, side effects such as dizziness, fatigue, headaches, decreased heart rate, low blood pressure, dyspepsia, skin rash, and abnormalities in liver function may occur. In severe cases, heart function deterioration or respiratory distress may arise, so immediately consult a doctor if any unusual symptoms are present. Long-term use requires regular monitoring of heart function, blood pressure, liver, and kidney function, and do not abruptly stop taking the medication; gradually reduce the dosage according to a doctor's instructions. Additionally, caution is advised while driving or operating machinery as dizziness or drowsiness may occur. This medication can interact with other drugs, especially those for hypertension, heart diseases, diabetes, sedatives, antidepressants, and anesthetics. Therefore, always consult a doctor or pharmacist before taking it with other medications. Pregnant or breastfeeding women should not take this medication, and safety for children and adolescents under 18 has not been established. In cases of overdose, there is a risk of severe low blood pressure, decreased heart rate, shock, and respiratory distress, so immediate medical attention is required.

• Dizziness
• headache
• fatigue
• weakness
• hallucinations
• confusion
• depression
• sleep disturbances
• nightmares
• psychosis

This medication is sensitive to light; it should be stored in a container that blocks light. Additionally, it is advisable to store the medication at room temperature between 1 to 30 degrees Celsius. By storing it this way, the efficacy and safety of the medication can be maintained.

Appearance

Round reddish-brown tablet

Package unit

100 tablets (10 tablets/PTP) X 10