Hawon Ceftriaxone Injection 2g (Ceftriaxone Sodium Hydrate)

Adult administration

As ceftriaxone, administer 1 to 2 g (potency) once daily by intravenous or intramuscular injection. For infections caused by severe pathogens or pathogens with moderate sensitivity, the dose can be increased to 4 g (potency) once daily. For gonorrhea treatment, a single intramuscular injection of 250 mg (potency) is recommended. To prevent infections before and after surgery, it is desirable to administer 1 to 2 g (potency) as a single dose 30 to 90 minutes before surgery.

Child administration

For infants and children under 12 years, administer 20 to 80 mg (potency) per kg of body weight once daily from 15 days to 12 years of age. For children over 50 kg, the adult dosage is to be administered.

This medication should not be mixed with calcium-containing solutions or other medications. In particular, when administered to newborns, combining this medication with calcium can result in precipitate formation and serious side effects. Patients with hypersensitivity to this medication or allergies to cephalosporin or penicillin antibiotics should not use it. Premature infants or newborns with bilirubin binding issues may be at risk if this medication is used. Patients with severe kidney disease may require dosage adjustments since the drug concentration may increase, and patients with a history of allergies should also be cautious. This medication can cause various side effects including diarrhea, rash, changes in blood cell counts, and increased liver enzymes; if any abnormal symptoms appear, the healthcare provider must be notified immediately. Severe allergic reactions or shock symptoms may occur; therefore, a medical history and skin reaction tests are recommended prior to administration, and the patient's condition should be closely monitored during the treatment. Regular tests for liver and kidney function and blood tests are advisable during the treatment with this medication. In cases of overdose, there is no specific antidote available, so treatment should be symptomatic, and caution should be exercised when driving or operating machinery due to dizziness and other side effects. Pregnant or lactating women should only use this medication cautiously if its safety is uncertain. It is advisable to avoid using this medication in children, especially newborns and premature infants, due to a higher risk of side effects. Elderly patients may experience more pronounced side effects due to decreased bodily functions, so careful observation during administration is required. This medication may interact with other drugs; therefore, if other medications are being taken, the healthcare provider must be informed. When administering, the medication must be given separately from calcium-containing solutions to prevent precipitation, and the infusion port should be thoroughly cleaned after administration. This medication should be used as soon as possible after preparation, and the prescribed temperature and duration should be strictly adhered to during storage.

Serious side effects

Urticaria, severe swelling (edema), difficulty breathing, severe allergic reactions, severe skin adverse reactions (erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis), liver abnormalities (jaundice), serious neurological symptoms (encephalopathy, seizures, confusion), severe edema or urination disorders (acute renal failure, urethral obstruction), anaphylaxis, anaphylactoid reactions

Mild side effects

• Eosinophilia
• leukopenia
• thrombocytopenia
• diarrhea
• rash
• increased liver enzymes
• genital fungal infections
• pseudomembranous colitis
• headache
• dizziness

Store this medication in a tightly sealed container to prevent air and humidity exposure, ideally at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the efficacy of the medication for a longer duration.

Appearance

A vial filled with white to light yellow crystalline powder

Package unit

10 vials/case