BC Vancomycin Hydrochloride Injection 1 Gram

Adult dosage

Adults receive an intravenous infusion of 500mg (as vancomycin) every 6 hours or 1g (as vancomycin) every 12 hours. For oral administration for the treatment of antidiarrheal antibiotic-associated pseudomembranous colitis caused by Clostridium difficile and ileocolitis, 500 to 2000mg should be divided into 3 to 4 doses over 7 to 10 days. The total daily dose should not exceed 2g.

Children's dosage

Children receive an intravenous injection of 10mg per kg of body weight every 6 hours. Infants receive an intravenous injection of 10 to 15mg per kg of body weight every 12 hours. For infants and newborns, an initial dose of 1mg per kg is recommended.

This medication should not be administered to patients who have experienced severe allergic reactions or shock from this drug or from peptide and aminoglycoside antibiotics. Additionally, it should be used cautiously in patients with hearing impairment or renal dysfunction, especially in premature infants, newborns, and the elderly. During the administration of this drug, various side effects may occur, including neurological symptoms, gastrointestinal issues, blood disorders, hearing loss, liver and kidney function abnormalities, and skin rashes, requiring close observation of the patient's condition. In particular, rapid infusion may cause reactions such as skin flushing or hypotension, so it is important to administer the drug slowly. Long-term use or overdosing may increase the risk of renal dysfunction or hearing impairment, thus regular examinations and monitoring are necessary. Use should be cautious in pregnant or breastfeeding women, and in the case of breastfeeding, it is preferable to discontinue breastfeeding if possible. This medication may interact with other drugs, particularly those that have neurotoxic or nephrotoxic properties, so caution is needed when co-administered. During treatment, regular serum tests and liver and kidney function tests should be conducted, and if any adverse reactions occur, the physician should be consulted immediately. Finally, this medication must be administered via intravenous injection; intramuscular injection or administration through other routes may cause tissue damage or necrosis.

Serious side effects

• Hives
• severe swelling
• chest tightness
• difficulty breathing
• cold sweat
• pallor
• severe rashes with high fever
• blisters
• skin peeling
• pain in mucous membranes of mouth/eyes

Mild side effects

• Loose stools
• diarrhea
• nausea
• vomiting
• abdominal pain
• decreased red blood cells
• decreased white blood cells
• decreased platelets
• increased eosinophils
• dizziness

This medication should be stored in a sealed container to prevent exposure to air, preferably at a temperature between 1 to 30 degrees Celsius. Proper storage will help maintain its efficacy.

Appearance

A white to light yellowish-brown freeze-dried powder contained in a colorless, transparent vial.

Package unit

10 vials