Cecil Tablet 250mg (Cefuroxime Axetil)

Adult dose

Dosage: For optimal absorption, this medicine should be taken after meals. 1) Most infections Administer 250mg twice daily. 2) Severe lower respiratory tract infections, pneumonia, severe infections, or suspected infections caused by less susceptible organisms Administer 500mg twice daily. 3) Urinary tract infections Administer 250mg twice daily. 4) Uncomplicated gonorrhea Administer 1g as a single dose. 5) Lyme disease Administer 500mg twice daily for 14 days (10~21 days). 3. Patients with renal impairment Cefuroxime is primarily excreted by the kidneys. To compensate for delayed excretion in patients with significant renal impairment, reducing the dose of cefuroxime as follows is recommended. ≥ 30 mL/min/1.73m2: No dose adjustment required (standard dose: 125mg-500mg twice daily) 10 - 29 mL/min/1.73m2: Administer a standard single dose every 24 hours < 10 mL/min/1.73m2: Administer a standard single dose every 48 hours Patients undergoing hemodialysis: Administer an additional standard single dose at the end of each dialysis session

Child dose

Children aged 12 years and older: Most infections — administer 250mg twice daily. Children aged 12 years and older: Severe lower respiratory tract infections, pneumonia, severe infections, or infections suspected to be caused by organisms with low susceptibility — administer 500mg twice daily. Children aged 12 years and older: Urinary tract infections — administer 250mg twice daily. Children aged 12 years and older: Uncomplicated gonorrhea — administer 1g as a single dose. Children aged 12 years and older: Lyme disease — administer 500mg twice daily for 14 days (10~21 days). Children under 12 years: Most infections — administer 125mg twice daily. Children aged 2 years and older: Otitis media, severe infections — administer 250mg twice daily. Children under 12 years: Lyme disease — administer 250mg twice daily for 14 days (10~21 days). There is insufficient experience with use in infants younger than 3 months. For the treatment of infections caused by Streptococcus pyogenes (Group A beta-hemolytic), this medicine should be administered for 7~10 days. This medicine must not be divided and is therefore not suitable for treating patients who cannot swallow tablets, such as infants and young children.

This medication should not be used in patients with hypersensitivity to cephalosporin antibiotics. Patients with a history of allergy to penicillin or other beta-lactam antibiotics, and those with a tendency to show allergic symptoms such as bronchial asthma, rash, or urticaria in themselves or their family should use it with caution. Patients with severely impaired kidney function or those who cannot take medications orally, elderly patients, or patients in poor health should be carefully monitored for vitamin K deficiency symptoms. While using this medication, mild side effects are mostly transient, but serious skin reactions, blood abnormalities, or liver dysfunction may rarely occur, and if any abnormal symptoms appear, medical advice should be sought immediately. During antibiotic treatment, excessive proliferation of Candida or disruption of the balance of beneficial gut bacteria may occur, leading to diarrhea or gastrointestinal disturbances, and serious colitis symptoms, such as pseudomembranous colitis, may arise. If diarrhea persists or abdominal pain worsens, administration should be stopped immediately and medical attention sought. This medication may cause dizziness, so caution is needed when driving or operating machinery. When used with other medications, it may affect kidney function, so it's crucial to inform healthcare providers of all medications being taken, and taking antacids concurrently may reduce effectiveness; it is advisable to take this medication with meals. Women who are pregnant or potentially pregnant should only use this medication if absolutely necessary, as its safety has not been fully confirmed. Caution is also needed while breastfeeding. This drug's safety has not been established in infants under three months, and it is preferable to avoid its use in this population. For children, due to its strong bitter taste, it is recommended to administer it in syrup form. Elderly patients may have reduced bodily functions, making side effects more likely, so dosage and intervals should be adjusted while carefully monitoring their condition. This medication may affect some clinical test results, so it is essential to inform healthcare providers that this medication is being taken before tests. Overdosing may lead to serious side effects such as seizures, and drug concentration can be reduced by hemodialysis or peritoneal dialysis. Finally, this medication should be stored out of reach of children and kept in its original container to prevent misuse or deterioration in quality.

• Candida overgrowth
• eosinophilia
• positive Coombs test
• thrombocytopenia
• leukopenia
• agranulocytosis
• anemia
• decrease in hemoglobin
• decrease in hematocrit
• hemolytic anemia

This medication should be stored in a tightly sealed container to prevent air and moisture from entering. It is best to store it at room temperature between 1 to 30 degrees Celsius.

Appearance

White rectangular film-coated tablet

Package unit

50 tablets (10 tablets/PTP × 5)