Famciclovir 750 mg Tablet

Adult dosage

1. Treatment of herpes zoster Adults: Administer famciclovir orally at a dose of 750 mg once daily for 7 days. Take it at the same time each day. It is preferable to start treatment as soon as symptoms appear after infection. 2. Patients with renal impairment: Because the creatinine clearance of this drug is reduced in patients with renal impairment, dose adjustments should be made with caution. The dosage and administration for these patients are as follows. 1) Treatment of herpes zoster Creatinine clearance (mL/min/1.73㎡) Dose 30–59 250 mg per dose, twice daily 10–29 250 mg per dose, once daily 2) If only serum creatinine is known, creatinine clearance can be calculated using the following formula. Men: {body weight (kg) × (140-age)}/ {72 × serum creatinine (mg/dL)} Women: 0.85 × the value calculated for men 3) Patients with renal impairment undergoing hemodialysis: For patients on hemodialysis, administration every 48 hours is preferable, taking the dialysis interval into account. Because 4 hours of hemodialysis reduces the plasma concentration of this drug by approximately 75%, administer the full dose of this drug immediately after dialysis. 3. Patients with hepatic impairment: No dose adjustment is required for patients with chronic compensated liver disease. There is insufficient treatment experience in patients with overt chronic decompensated liver disease; therefore, a clear recommended dose has not been established.

This drug should not be used in patients with known allergies to specific components. Additionally, it contains lactose, so it is recommended that patients with lactose intolerance or genetic metabolic disorders avoid it. Patients with reduced kidney function should exercise special caution when using this drug, and dosage adjustments may be necessary. This drug does not completely cure genital herpes, and patients should avoid sexual contact while symptoms are present. If dizziness or drowsiness occurs during use, driving or operating machinery should be avoided. Patients with mild to moderate liver dysfunction do not require special dosage adjustments, but safety has not been established in patients with severe liver impairment. There may be interactions when taken with other medications, so caution is especially needed when taken with probenecid or lamotrigine. Women who are pregnant or breastfeeding should carefully discuss the need for this medication with their healthcare provider before use. Children under 18 years of age are not recommended for use as safety and efficacy have not been sufficiently studied. Generally, the elderly do not require dosage adjustments, but if kidney function is impaired, dosage should be adjusted. In case of overdose, immediate medical attention is required, and hemodialysis may be helpful. This drug should be stored in a dry place below 30 degrees Celsius and out of reach of children. Moreover, transferring from the original container to another container is not recommended as it may negatively affect quality.

• headache
• nausea
• thrombocytopenia
• leukopenia
• neutropenia
• dizziness
• confusion
• drowsiness
• hallucination
• palpitations

This medication is sensitive to air and moisture, so it must be stored in a sealed container. Additionally, it should be kept in a cool, dry place below 30 degrees Celsius to maintain its efficacy.

Appearance

White, oval-shaped, film-coated tablet

Package unit

Company packaging unit