Crestor 5 mg (Rosuvastatin Calcium)

Adult dose

Administer 5 mg once daily as the initial dosage, regardless of meals, at any time of the day. If necessary, the maintenance dosage can be adjusted to 10 mg once daily, and up to a maximum of 20 mg once daily can be increased at intervals of 4 weeks or more based on LDL cholesterol levels and patient response.

Child dose

Children with heterozygous familial hypercholesterolemia (ages 10 to 17 years) are administered dosage ranging from 5 mg to 20 mg once daily. The dosage should be adjusted according to the recommended therapeutic target at intervals of 4 weeks or more.

It is crucial not to administer this medication to certain patients. For example, patients who are allergic to any of its components, have severe liver dysfunction, or have muscle diseases should not take this medication. Additionally, patients with significantly impaired kidney function, women who are pregnant or breastfeeding, and fertile women who do not use adequate contraception should not use this medication. Patients at high risk of muscle problems should avoid high doses of this medication, and those with certain genetic disorders such as lactose intolerance should not take it. Regular monitoring of liver function and muscle status is required while on this medication. Particularly, individuals with a history of liver disease or those who consume alcohol excessively should exercise extra caution, and if symptoms like muscle pain or weakness occur, they should notify their doctor immediately. This medication may interact with other drugs; therefore, patients must inform their healthcare provider about any other medications they are taking. Women of childbearing potential should ensure thorough contraception while taking this medication and should discontinue usage immediately if pregnancy is confirmed. In case of overdose, there are no specific antidotes, and appropriate treatment and testing based on symptoms are necessary. Furthermore, while this medication does not significantly impact the ability to drive or operate machinery, caution should be exercised as dizziness may occur. Lastly, this medication may rarely cause serious skin reactions, liver damage, or muscle problems in some patients; if any unusual symptoms arise, immediate consultation with a healthcare provider is essential.

Serious side effects

Urticaria, hypersensitivity reactions including angioedema, pancreatitis, myopathy (including myositis), rhabdomyolysis, thrombocytopenia, jaundice, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), immune-mediated necrotizing myopathy, hematuria, swelling, cough, dyspnea, severe muscle weakness, ocular myasthenia, fatal and non-fatal liver failure, acute renal failure, oliguria, memory loss, peripheral neuropathy

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• weakness
• diarrhea

This medication should be stored in a tightly closed container to protect it from exposure to air and moisture. It is also advisable to store it at room temperature between 1 degree and 30 degrees Celsius. This way, the ingredients of the medication remain unchanged and safe for use.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle, 30 tablets (15 tablets/PTP×2)