Clarosin Tablet (Clarithromycin)

Adult dosage

Adults: The usual dose is 250mg (potency) of clarithromycin twice daily. For severe infections, the dose is 500mg (potency) twice daily. The usual treatment duration is 7～14 days. For patients with renal failure and a creatinine clearance of 30mL/min or less, the dose should be reduced by half. That is, 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer for more than 14 days to these patients. Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcer: Administer 500mg (potency) of this medicine 3 times daily with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for an additional 14 days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children aged 12 years and older: same as adults For children under 12 years of age, use clarithromycin dry syrup.

This medication should not be administered to certain patients. For example, those who are allergic to the ingredients of this medication or have had hypersensitive reactions to similar classes of antibiotics should not use it. Additionally, patients taking certain heart-related medications, those with heart diseases, and those with severe liver or kidney impairments should avoid this medication for safety. Pregnant or breastfeeding women should also refrain from taking this medication. This medication can interact with various drugs, so if you are taking other medications, be sure to consult a healthcare professional. This medication can lead to a variety of side effects. Rarely, serious allergic reactions or skin responses, liver function abnormalities, kidney dysfunction, and cardiac arrhythmias may occur, so if any symptoms arise, you must inform healthcare personnel immediately. Moreover, symptoms such as gastrointestinal disturbances, central nervous system symptoms, or hearing anomalies have also been reported, so caution is necessary. When using this medication, it is important to confirm the susceptibility of the bacteria to prevent the emergence of resistant strains and to take it only for the necessary duration. If diarrhea or abdominal pain persists after antibiotic use, immediate treatment should be sought due to the possibility of pseudomembranous colitis. Patients with impaired liver or kidney function, the elderly, those with heart disease, etc., may require dosage adjustment or interval changes, and should follow the guidance of healthcare personnel. It is generally advised that pregnant or breastfeeding women do not take this medication; if it must be taken, professional consultation is essential. During the period of taking this medication, symptoms such as dizziness or confusion may occur when driving or operating machinery, so caution is necessary. In cases of overdose, gastrointestinal disturbances or neurological abnormalities may occur, so it is vital to adhere to the prescribed dosage, and if any abnormal symptoms arise, immediate medical attention is necessary. This medication requires proper storage and should be kept in a light-blocking, tightly sealed container. Additionally, it is important to store it at room temperature between 1 to 30 degrees Celsius to maintain its effectiveness over time.

Shock, anaphylactic symptoms, dyspnea, convulsions, flushing, rash, itching, urticaria, skin flushing, angioedema, joint swelling, drug rash, abdominal bloating, nausea, vomiting, dyspepsia, abdominal pain, discomfort, flatulence, diarrhea, oral mucosal erosion, upper abdominal pain, convulsive forms, dry mouth, transient tooth discoloration, pancreatitis, increased amylase, taste disturbances, anorexia, constipation, discoloration of stool, pseudomembranous colitis, hemorrhagic colitis, fever, cough, eosinophilia, eosinophilic lung infiltration, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, orientation disorder, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash with eosinophilia and systemic symptoms, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, elevated BUN, interstitial nephritis, kidney failure, rhabdomyolysis, myalgia, malaise, elevated CPK, elevated serum myoglobin, elevated urinary myoglobin, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, fatigue, headache, dysgeusia, auditory loss, paresthesia, arthralgia, myalgia, olfactory impairment, tinnitus, auditory impairment, hypoglycemia, purpuric rash, acute generalized exanthematous pustulosis, muscle spasms, musculoskeletal rigidity, myopathy, elevated blood urea nitrogen, nephritis, phlebitis at the injection site, pain at the injection site, inflammation at the injection site, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, abnormal urine color

This medication is sensitive to light, so it should be stored in a light-blocking, tightly sealed container. Additionally, it is important to store it at room temperature, maintaining a temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness over time.

Appearance

Yellow oval film-coated tablet with a vanilla flavor

Package unit

30 tablets/bottle, 100 tablets/bottle