Heracin Tablet 250 Milligrams (Clarithromycin)

Adult dose

○ Adults : The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual treatment duration is 7～14 days. In patients with renal impairment and a creatinine clearance of 30mL/min or less, the dose should be reduced by half. That is, administer 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer this medicine to these patients for more than 14 days. ○ Mycobacterial infections : Administer 500mg (potency) twice daily. In this case, it must be administered in combination with other antimycobacterial agents, such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcers : Administer this medicine 500mg (potency) three times daily in combination with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) three times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Child dose

○ Children 12 years of age and older: Same as adults. For children under 12 years of age, use clarithromycin dry syrup.

This medication should not be administered to patients with specific allergic reactions or certain heart diseases, liver dysfunction, and kidney disorders. It should also not be used by women who are pregnant or breastfeeding. This medication may interact with other drugs, so it is essential to inform your doctor or pharmacist about any medications you are taking. During administration, careful observation for unusual symptoms such as allergic reactions, cardiac arrhythmias, and abnormal liver function is required. Long-term or high-dose use may cause hearing impairment or tinnitus, so caution is necessary. This medication can cause various side effects including gastrointestinal disturbances, skin rashes, or neurological disorders, and immediate consultation with medical personnel is required if such symptoms appear. In particular, if severe allergic reactions or skin abnormalities occur, administration should be stopped immediately and appropriate treatment should be sought. Elderly patients or those with impaired kidney and liver functions may require dose adjustments, and they should follow medical advice. If persistent diarrhea or abdominal pain occurs during taking this medication, notify medical personnel immediately due to the possibility of pseudomembranous colitis. Additionally, this medication contains lactose, so patients with lactose intolerance should be cautious. During the use of this medication, dizziness or confusion may occur when driving or operating machinery, so care must be taken. In case of overdose, gastrointestinal symptoms or central nervous system abnormalities may occur; immediate medical assistance should be sought. This medication should only be used for the prescribed duration as directed by a physician, and should not be discontinued or dosage altered arbitrarily.

Shock, anaphylactic symptoms, dyspnea, convulsions, redness, rash, itching, hives, mild skin redness, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, malaise, flatulence, diarrhea, oral mucosal erosion, upper abdominal pain, dryness of mouth, transient tooth discoloration, pancreatitis, increased amylase, taste disturbance, loss of appetite, constipation, discoloration of stools, pseudomembranous colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic pulmonary infiltration, interstitial pneumonia, chronic bronchitis, acute exacerbation of acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash accompanied by eosinophilia and systemic symptoms, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, impaired liver function, liver failure, fulminant hepatitis, increased AST, increased ALT, increased γ-GTP, increased LDH, increased ALP, elevated total bilirubin, increased serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, fatigue, headache, taste disorder, hearing loss, dysesthesia, arthralgia, myalgia, olfactory dysfunction, hypoglycemia, tinnitus, auditory impairment, purpuric rash, acute generalized exanthematous pustulosis, vasodilation, bleeding, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, tooth discoloration, rash, hyperhidrosis, vesicular dermatitis, papular rash, acne, Henoch-Schonlein purpura, muscle spasms, musculoskeletal rigidity, myopathy, elevated blood urea, nephritis, injection site phlebitis, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, increased alkaline phosphatase in the blood, increased lactate dehydrogenase in the blood, increased international normalized ratio, prolonged prothrombin time, urine color abnormality

This medication should be stored in a container that blocks light and air, at a temperature between 15 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle