Famster Tablet 750 mg (Famciclovir)

Adult dose

1. Treatment of herpes zoster Adults: Famciclovir is administered orally at 750 mg once daily for 7 days. Take it at the same time each day. It is preferable to start treatment as soon as symptoms appear after infection. 2. Patients with renal impairment: Because the clearance of this drug is reduced in patients with renal impairment, dose adjustment should be undertaken with caution. The dosage and administration for these patients are as follows. 1) Treatment of herpes zoster Creatinine clearance (mL/min/1.73㎡) 30～59: 250 mg per dose twice daily 10～29: 250 mg per dose once daily 2) If only serum creatinine is known, creatinine clearance can be calculated using the following formula. Men: {body weight (kg) × (140-age)}/ {72 × serum creatinine (mg/dL)} Women: 0.85 × the value calculated for men 3) Patients with renal impairment undergoing hemodialysis: For patients undergoing hemodialysis, administration every 48 hours is preferable, taking the interval between dialysis sessions into account. Four hours of hemodialysis reduces the plasma concentration of this drug by approximately 75%; therefore, administer the full dose of this drug immediately after dialysis. 3. Patients with hepatic impairment: No dose adjustment is necessary for patients with chronic compensated liver disease. There is insufficient treatment experience in patients with overt chronic decompensated liver disease; therefore, a clear recommended dose has not been established.

This medication should not be used in patients who have had allergic reactions to this drug or its ingredients. This drug contains lactose; therefore, patients with lactose intolerance or certain genetic metabolic disorders should avoid taking it. Patients with reduced kidney function should be cautious when using this drug and may require dose adjustment. This medication may cause mild side effects such as headache or nausea, but they are usually of minor severity. Immunocompromised patients can also generally use this drug safely, but rare side effects like a decrease in blood cell count have been reported. Especially in elderly patients, neurological side effects such as headache, dizziness, drowsiness, and hallucinations may rarely occur. Gastrointestinal side effects such as nausea or vomiting may occur, and reactions like liver function abnormalities or skin rashes have also been reported rarely. In patients with poor kidney function, there is an increased risk of acute renal failure, so dose adjustments are important. This drug does not completely cure genital herpes, so it is advisable to avoid sexual contact during symptomatic periods and to initiate treatment immediately upon recurrence. If dizziness or drowsiness occurs during use, it is advised to refrain from driving or operating machinery. For patients with poor liver function, if kidney function is normal, no special dose adjustment is needed. This drug has minimal serious interactions with other medications; however, changes in blood concentration may occur with some drugs related to excretion pathways. The safety of use during pregnancy has not been fully established; therefore, women who are pregnant or may become pregnant should use it carefully. For nursing mothers, since this drug may be excreted in breast milk, it should be administered after considering the benefits and risks. Its safety and efficacy in children under 18 years have not been established, so its use is not recommended. In the case of an overdose, there may not be specific symptoms; however, appropriate treatment such as dialysis should be administered if needed. This drug should be stored in a dry place at temperatures below 30 degrees Celsius, and care should be taken to keep it out of reach of children. Transferring to another container is not advisable as it can negatively affect the quality of the drug.

• Headache
• nausea
• thrombocytopenia
• leukopenia
• neutropenia
• confusion
• dizziness
• drowsiness
• hallucinations
• vomiting

This medication should be stored in a tightly sealed container to prevent moisture and kept in a dry place at temperatures below 30 degrees Celsius. Storing it in this way helps maintain the potency of the drug.

Appearance

White oval film-coated tablet

Package unit

7 tablets/PTP