Medication info
Alprazolam Tablet 0.25 mg

Alprazolam Tablet 0.25 mg

Prescription medicationTabletOral
Ingredient · strength
Alprazolam›0.25mg / 1 tablet
Manufacturer / importer
Korea Pharma Co., Ltd.
Appearance
White oval tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 200410831 · Approved 2004.08.27 · Insurance code 653001570

Summary

Main use
Relief of symptoms of anxiety (anxiety disorders with accompanying depression), panic disorder, and psychosomatic disorders
Who takes it
Adults
Adult dose
Determine the dose individually to obtain the maximum benefit. The usual daily doses listed below are suitable for most patients, although higher doses may be required. In such cases, increase the dose slowly to avoid adverse effects. The risk of dependence may increase with the dose and duration of treatment. Therefore, use the lowest effective dose for the shortest possible duration and frequently reassess the need to continue treatment. ○ Adults 1. For alprazolam, the initial dose is 0.25-0.5㎎ 3 times daily, with a maximum dose of 4㎎ per day. For elderly patients, patients with hepatic impairment, and debilitated patients, the initial dose is 0.25㎎ 2-3 times daily. Reduce the dose if adverse effects occur at the initial dose. 2. Psychosomatic disorders Administer 1.2㎎ per day of this medicine orally in 3 divided doses. If increasing the dose, increase it slowly up to a maximum of 2.4㎎ per day, administered orally in 3-4 divided doses. For elderly patients, the initial dose is 0.4㎎ 1-2 times daily, with a maximum dose of 1.2㎎ per day. 3. Panic disorder Start with 0.5㎎ of this medicine and, depending on the patient's response to treatment, increase the dose by no more than 1㎎ at intervals of 3-4 days, to an average daily dose of 5-6㎎ divided into 3-4 doses. When discontinuing treatment, reduce the dose by no more than 0.5㎎, usually at 3-day intervals; lower doses may sometimes be required.

Ingredients

Manufacturer
Korea Pharma Co., Ltd.

Efficacy & effects

Relief of symptoms of anxiety (anxiety disorders with accompanying depression), panic disorder, and psychosomatic disorders

  • Anxiety disorders
  • anxiety symptoms
  • anxiety
  • tension
  • depression
  • sleep disorders
  • panic disorder
View approved original text

This medication is used for the treatment of anxiety-related disorders such as anxiety disorder and panic disorder. It also helps alleviate anxiety symptoms associated with depression. It is effective in improving anxiety, tension, depression, and sleep disorders caused by psychosomatic disorders. It is used to stabilize and improve various anxiety-related symptoms.

How to take

Adult dose

Determine the dose individually to obtain the maximum benefit. The usual daily doses listed below are suitable for most patients, although higher doses may be required. In such cases, increase the dose slowly to avoid adverse effects. The risk of dependence may increase with the dose and duration of treatment. Therefore, use the lowest effective dose for the shortest possible duration and frequently reassess the need to continue treatment. ○ Adults 1. For alprazolam, the initial dose is 0.25-0.5㎎ 3 times daily, with a maximum dose of 4㎎ per day. For elderly patients, patients with hepatic impairment, and debilitated patients, the initial dose is 0.25㎎ 2-3 times daily. Reduce the dose if adverse effects occur at the initial dose. 2. Psychosomatic disorders Administer 1.2㎎ per day of this medicine orally in 3 divided doses. If increasing the dose, increase it slowly up to a maximum of 2.4㎎ per day, administered orally in 3-4 divided doses. For elderly patients, the initial dose is 0.4㎎ 1-2 times daily, with a maximum dose of 1.2㎎ per day. 3. Panic disorder Start with 0.5㎎ of this medicine and, depending on the patient's response to treatment, increase the dose by no more than 1㎎ at intervals of 3-4 days, to an average daily dose of 5-6㎎ divided into 3-4 doses. When discontinuing treatment, reduce the dose by no more than 0.5㎎, usually at 3-day intervals; lower doses may sometimes be required.

Precautions

This medication belongs to the benzodiazepine class and is used for sedation and anxiety relief. Co-administration with narcotics can lead to respiratory depression or, in severe cases, coma, so it should be taken only at the lowest dose for a short period when absolutely necessary. The medication has a risk of abuse, so it should be taken exactly as prescribed by a doctor, and any remaining medication should be stored or disposed of safely. It should not be taken if there is an allergy to this medication or if there are acute angle-closure glaucoma, severe myasthenia gravis, severe respiratory failure, severe liver dysfunction, or certain psychiatric disorders. Patients with heart, liver, or kidney issues, elderly patients, and those with slight respiratory problems should take this medication with special caution, and formulations containing allergens should be used with care. Withdrawal symptoms may occur upon discontinuation of this medication, so do not stop suddenly; rather, taper off gradually according to a doctor’s instructions. Drowsiness or decreased concentration may occur, so avoid driving or operating hazardous machinery while taking this medication. This medication is metabolized in the liver, so be cautious if taken with other drugs that affect liver function or with alcohol, as this can exacerbate side effects. It is advisable to avoid using this medication during pregnancy, especially during the last three months, and during breastfeeding. Safety and effectiveness have not been established in children under 18, so it is preferable not to use it in this age group. In cases of overdose, severe drowsiness, coma, and respiratory depression may occur, requiring immediate treatment at a hospital. Store this medication out of reach of children and keep it in its original packaging for safety.

Side effects

  • Mild discomfort
  • insomnia
  • abdominal and muscle cramps
  • vomiting
  • sweating
  • tremors
  • convulsions
  • seizures
  • agitation
  • increased muscle stiffness
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  • sleep disturbances
  • hallucinations
  • restlessness
  • anger
  • irritability
  • aggressive behavior
  • hostile behavior
  • hypersensitivity
  • resentment
  • obsessive thoughts
  • drowsiness
  • ataxia
  • memory impairment
  • speech disorders
  • dizziness
  • headaches
  • disturbance of equilibrium
  • impairments in coordination
  • attention disorders
  • hypersomnia
  • somnolence
  • tremors
  • amnesia
  • autonomic nervous system imbalance
  • muscle tension abnormalities
  • blurred vision
  • constipation
  • dry mouth
  • nausea
  • hepatitis
  • liver dysfunction
  • jaundice
  • dermatitis
  • vascular edema
  • phototoxic reactions
  • muscle weakness
  • urinary incontinence
  • urinary retention
  • sexual dysfunction
  • menstrual irregularities
  • fatigue
  • drug withdrawal syndrome
  • peripheral edema
  • weight loss
  • weight gain
  • increased intraocular pressure
  • drowsiness
  • mild headache
  • depression
  • confusion
  • insomnia
  • neuroticism
  • syncope
  • dizziness
  • inability to maintain a sitting position
  • thirst
  • diarrhea
  • increased saliva production
  • tachycardia
  • palpitation
  • hypotension
  • nasal congestion
  • acceleration
  • tremors
  • dermatitis
  • rash
  • increased appetite
  • decreased appetite
  • urination disorders
  • menstrual disorders
  • edema
  • infection
  • fatigue
  • hypersensitivity
  • insomnia
  • involuntary movement disorders
  • cognitive impairments
  • weakness
  • disinhibition
  • sensory disturbances
  • polyuria
  • vascular movement disturbances
  • unreality
  • abnormal dreams
  • panic
  • warm sensation
  • decreased saliva production
  • abdominal discomfort
  • chest pain
  • hyperventilation
  • upper respiratory infection
  • tinnitus
  • muscle cramps
  • muscle rigidity
  • sweating
  • seizures
  • depersonalization
  • taste changes
  • double vision
  • increased bilirubin
  • elevated liver enzymes
  • gynecomastia
  • excessive milk secretion
  • delirium
  • apathy
  • hyperactivity
  • dyspepsia
  • muscle weakness
  • chest pain
  • fatigue
  • falling
  • ataxia
  • impaired motor coordination
  • incoherent speech
  • coma
  • respiratory depression

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light and should be stored in a special container that blocks light. The medication should be kept at room temperature that is not excessively hot or cold, specifically between 1 degree and 30 degrees Celsius for safe and effective use.

Appearance and packaging

Appearance

White oval tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.