Medication info
Geneuone Lomefloxcin Hydrochloride Tablets

Geneuone Lomefloxcin Hydrochloride Tablets

Prescription medicationTabletOral
Ingredient · strength
Lomefloxacin Hydrochloride›441.6mg / 1 tablet
Manufacturer / importer
Genewon Science Co., Ltd.
Appearance
White oval film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 200404647 · Notified 2004.05.29 · Insurance code 671701970

Summary

Main use
Treatment of urinary and reproductive tract, intestinal, respiratory and ear, nose, and throat, skin, eye, and dental infections
Who takes it
Adults
Adult dose
1. Administer 100 ~ 200 mg of lomefloxacin orally 2 ~ 3 times daily. 2. However, for acute exacerbations of chronic obstructive pulmonary disease, including chronic bronchitis, the usual adult dose is 400 mg of this medicine orally once daily, with or without food. The duration of treatment varies according to the severity of the infection, but is usually up to 14 days. Treatment should be continued for at least 2 days after the infection symptoms have resolved. 3. Patients with renal impairment 1) In patients with a creatinine clearance of less than 30 mL per minute, administer an initial dose of 400 mg of this medicine once, followed by 200 mg once daily starting the next day. 2) In patients on hemodialysis, administer an initial dose of 400 mg of this medicine, followed by 200 mg once daily starting the next day. 3) No dose adjustment is necessary in patients with hepatic impairment; adjust the dose according to renal function.

Ingredients

Manufacturer
Genewon Science Co., Ltd.

Efficacy & effects

Treatment of urinary and reproductive tract, intestinal, respiratory and ear, nose, and throat, skin, eye, and dental infections

  • Folliculitis
  • pustular acne
  • abscess
  • furuncle
  • superficial soft tissue infections
  • cellulitis
  • lymphangitis
  • digital inflammation
  • purulent paronychia
  • subcutaneous abscess
  • suppurative hidradenitis
  • acne conglobata
View approved original text

This drug is effective against various types of bacteria and is used to treat different infections. For example, it is used for infections of the skin and soft tissues, acute exacerbations of chronic bronchitis and chronic obstructive pulmonary disease, community-acquired pneumonia, urinary tract infections, bacterial gastroenteritis, infections of the female reproductive system, infections of the eyes and ears, and dental infections. As a fluoroquinolone, there is a potential for serious adverse reactions, and it is recommended to use this drug only when there are no alternative treatments for acute bacterial sinusitis, acute exacerbations of chronic bronchitis including chronic obstructive pulmonary disease, simple urinary tract infections, and acute otitis media. Overall, this drug is very useful for treating a variety of bacterial infections.

How to take

Adult dose

1. Administer 100 ~ 200 mg of lomefloxacin orally 2 ~ 3 times daily. 2. However, for acute exacerbations of chronic obstructive pulmonary disease, including chronic bronchitis, the usual adult dose is 400 mg of this medicine orally once daily, with or without food. The duration of treatment varies according to the severity of the infection, but is usually up to 14 days. Treatment should be continued for at least 2 days after the infection symptoms have resolved. 3. Patients with renal impairment 1) In patients with a creatinine clearance of less than 30 mL per minute, administer an initial dose of 400 mg of this medicine once, followed by 200 mg once daily starting the next day. 2) In patients on hemodialysis, administer an initial dose of 400 mg of this medicine, followed by 200 mg once daily starting the next day. 3) No dose adjustment is necessary in patients with hepatic impairment; adjust the dose according to renal function.

Precautions

This drug can cause serious side effects such as tendonitis or tendon rupture, so use should be discontinued immediately if such symptoms occur. This drug should not be used in patients with myasthenia gravis as it may worsen symptoms. This drug is used only for the treatment of specific bacterial infections and should be administered only when no alternative treatment is available. Caution is needed in elderly patients, those with impaired kidney function, or when taken with corticosteroids, as the risk of tendon damage may increase. This drug is not recommended for use in growing adolescents under 18 years of age, pregnant women or women who may become pregnant, and patients allergic to this drug or similar medications. Patients with epilepsy or heart and aortic diseases should be cautious when using this drug. During treatment with this drug, allergic reactions, skin rash, severe gastrointestinal disorders, liver or kidney dysfunction, or neurological symptoms may occur, so consult a doctor immediately if any abnormal symptoms arise. Excessive exposure to sunlight may cause skin reactions, so it is advisable to avoid strong sunlight or UV exposure during treatment. This drug may cause dizziness or drowsiness, so caution should be exercised when driving or operating machinery. Diabetic patients taking blood sugar control medications should frequently check blood sugar levels as fluctuations may occur. This drug can interact with other medications, so inform your healthcare provider of any other medications you are taking. Pregnant or breastfeeding women should not use this drug, and breastfeeding should be discontinued during treatment. In cases of overdose, appropriate emergency measures such as inducing vomiting or gastric lavage may be required, so immediate medical attention should be sought.

Side effects

  • Tendinitis
  • tendon rupture
  • peripheral neuropathy
  • central nervous system effects
  • exacerbation of myasthenia gravis
  • anaphylactic shock
  • anaphylactoid reaction
  • rash
  • urticaria
  • erythema
Show 121 more
  • pruritus
  • edema
  • angioedema
  • conjunctival congestion
  • vesicles
  • erythema
  • photosensitivity reaction
  • exfoliative dermatitis
  • hyperpigmentation
  • Stevens-Johnson syndrome
  • toxic epidermal necrolysis
  • hypokalemia
  • elevated BUN
  • elevated serum creatinine
  • acute renal failure
  • elevated AST
  • elevated ALT
  • elevated ALP
  • elevated serum bilirubin
  • gastrointestinal inflammation
  • oral candidiasis
  • constipation
  • diarrhea
  • anorexia
  • dyspepsia
  • vomiting
  • nausea
  • abdominal pain
  • stomatitis
  • angular cheilitis
  • oral psoriasis
  • gastric discomfort
  • abdominal distension
  • gastrointestinal disorder
  • dry mouth
  • bloody stools
  • neuritis
  • drowsiness
  • excitement
  • appetite changes
  • confusion
  • personality loss
  • depression
  • delirium
  • hallucinations
  • paranoia
  • anxiety
  • disorientation
  • attention deficit
  • memory impairment
  • sleep disorders
  • decreased concentration
  • headache
  • dizziness
  • insomnia
  • tremors
  • nightmares
  • dyspnea
  • respiratory infections
  • nosebleeds
  • influenza
  • other respiratory disorders
  • monocytes increase
  • elevated ESR
  • leukopenia
  • thrombocytopenia
  • eosinophilia
  • erythropenia
  • decreased hemoglobin
  • decreased hematocrit
  • hemolytic anemia
  • sensory disturbances
  • seizures
  • sweating
  • flushing
  • edema
  • hypertension
  • coma
  • tachycardia
  • arrhythmia
  • extrasystole
  • phlebitis
  • palpitations
  • angina
  • cerebral thrombosis
  • prolonged QT interval
  • ventricular tachycardia
  • leg cramps
  • arthralgia
  • Achilles tendon rupture
  • myalgia
  • weakness
  • elevated creatine kinase
  • elevated myoglobin
  • rhabdomyolysis
  • tinnitus
  • vaginitis
  • vaginal discharge
  • intermenstrual bleeding
  • vaginal candidiasis
  • orchitis
  • fatigue
  • abdominal pain
  • weakness
  • anxiety
  • coldness in the face or hands
  • malaise
  • heat sensation
  • lymphedema
  • loss of taste
  • visual impairment
  • gout
  • thirst
  • palatal swelling
  • hypoglycemia
  • polyuria
  • laryngeal and pulmonary edema
  • aortic aneurysm
  • aortic dissection
  • cardiac valve regurgitation
  • cardiac valve insufficiency

Not everyone experiences these, and they can vary from person to person.

Storage

This drug should be stored in a tightly closed container that can block light and kept at room temperature between 1 °C and 30 °C. Storing it this way can maintain the drug's effectiveness.

Appearance and packaging

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.