Cepharincapsule (Cefaclor Hydrate)

Adult dose

Once administer 250mg (potency) of cefaclor hydrate orally every 8 hours. In the case of severe infections (such as pneumonia) and low-sensitivity infections, the dosage may be doubled. For acute gonococcal urethritis, this medication may be given in combination with 3g of the drug and 1g of probenecid as a single dose.

Child dose

Administer 20mg (potency) per kg of body weight per day divided every 8 hours. For severe infections, otitis media, and infections with low sensitivity, 40mg (potency) per kg of body weight can be administered, up to a maximum dose of:

This drug acts by binding to specific proteins to hinder the synthesis of bacterial cell walls, thereby killing bacteria. It should never be administered to patients who have previously experienced serious allergic reactions or shock from this medication. Patients with a history of allergy to this drug or cephalosporin antibiotics should not be administered this drug either. Caution is necessary when administering to patients with a history of allergy to penicillin antibiotics or those who are prone to allergic symptoms such as asthma, rash, or urticaria. Patients with severe kidney disease, elderly patients, those in poor general condition, or those unable to take orally require careful consideration when using this drug. Patients with gastrointestinal diseases, particularly those with a history of colitis, should also be administered with caution. Serious allergic reactions such as shock or anaphylaxis may occur during the administration of this drug; if symptoms occur, administration should be immediately stopped, and appropriate treatment should be sought. Severe skin reactions such as Stevens-Johnson syndrome or toxic epidermal necrolysis may occur, so skin condition should be closely monitored. Blood test results may show abnormalities, so regular checks on the blood status are essential, and administration should be stopped if abnormalities are detected. Since this drug may affect liver or kidney function, regular liver and kidney function tests should be performed, and administration should be stopped if abnormalities are found. Gastrointestinal side effects may include diarrhea, abdominal pain, nausea, vomiting, and in rare cases, serious colitis like pseudomembranous colitis may occur, requiring immediate notification if symptoms appear. Respiratory symptoms such as interstitial pneumonia or eosinophilic pulmonary infiltrates may rarely occur, so alert medical personnel immediately if breathing difficulties or coughing arise. Central nervous system symptoms such as restlessness, anxiety, dizziness, hallucinations, or drowsiness may rarely present, requiring careful observation. Oral inflammation or candidiasis may develop during the use of this drug, so the condition of the mouth should be checked as well. A tendency for bleeding may appear due to vitamin K deficiency; therefore, attention to bleeding symptoms is necessary, and blood tests should be performed if needed. This drug may interact with other medications, so consultation with healthcare professionals is necessary, especially when used with probenecid, drugs affecting kidney function, anticoagulants, and oral contraceptives. Pregnant or potentially pregnant women should only use this medication when the benefits outweigh the risks, as its safety during pregnancy is not guaranteed. Breastfeeding women should use this medication with caution, as it may pass into breast milk, and the effects on the infant should be observed. Safety and efficacy in neonates under 1 month have not been established, so it is advisable not to use it in this age group. Elderly patients may experience adverse reactions more easily due to decreased bodily function, thus requiring dosage adjustments and monitoring of their condition. During the use of this drug, positive results may appear in some tests, requiring careful interpretation of the test results.

Serious side effects

• Urticaria
• edema
• dyspnea
• shock
• anaphylactic symptoms
• severe allergic reactions
• Stevens-Johnson syndrome
• toxic epidermal necrolysis
• liver dysfunction symptoms
• jaundice

Mild side effects

• Generalized flushing
• peripheral edema
• sensory disturbances
• syncope
• hypertension
• vasodilation
• rash
• itching
• fever
• lymphadenopathy

This drug is light-sensitive, so it should be stored in a container that does not allow light in. Additionally, it is best stored at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the drug's effectiveness and safety.

Appearance

A hard capsule with a purple upper body and a white lower body filled with crystalline powder that is white or yellowish-white.

Package unit

30 capsules/bottle, 300 capsules/bottle