Limaclol Tablets (Clarithromycin)

Adult dose

Adults: The usual dose of clarithromycin is 250mg (potency) twice daily; for severe infections, administer 500mg (potency) twice daily. The usual treatment duration is 7～14 days. In patients with renal impairment and creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer for more than 14 days to these patients. Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcer: Administer 500mg (potency) of this medicine 3 times daily with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) 3 times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Child dose

Children 12 years and older: Same as adults Children under 12 years: Use clarithromycin dry syrup.

This medication should not be used in patients who are allergic to any of its components or have experienced hypersensitivity to similar class antibiotics in the past. Caution is advised as using this medication with drugs that can cause heart rhythm abnormalities may be dangerous, so patients currently taking such medications must be careful. Patients with severely impaired liver or kidney function should use this medication cautiously as it may affect its metabolism and excretion. It is advisable for pregnant or breastfeeding women not to take this medication; if unavoidable, it should be used after consulting a professional. This medication may rarely cause serious allergic reactions or skin rashes, liver dysfunction, gastrointestinal disturbances, neurological symptoms, and if any abnormal symptoms occur, discontinuation and consultation with medical personnel should be performed immediately. Diarrhea or pseudomembranous colitis may occur due to antibiotic use leading to intestinal bacterial imbalance, so persistent diarrhea symptoms must be reported immediately. This medication may interact with various other drugs, so patients currently taking other medications should inform their healthcare provider, and if necessary, monitoring of drug concentrations or dosage adjustments may be required. Elderly patients and those with weakened immunity should exercise greater caution as the risk of side effects is higher with this medication, and regular check-ups are recommended. In case of overdose, gastrointestinal disturbances or central nervous system symptoms may occur, so it is imperative to adhere to the prescribed dosage and to visit a medical institution immediately if abnormal symptoms arise. This medication should be stored away from direct sunlight and is best kept at room temperature, while refrigeration should be avoided.

Shock, anaphylactic symptoms, shortness of breath, seizures, redness, rash, itching, hives, skin erythema, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, malaise, flatulence, diarrhea, oral mucosal erosion, epigastric pain, thirst, transient tooth discoloration, pancreatitis, increased amylase, taste disturbances, loss of appetite, constipation, fecal discoloration, pseudomembranous colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic lung infiltrate, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, seizures, tremors, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzyme levels, liver dysfunction, hepatic failure, fulminant hepatitis, elevated AST, elevated ALT, increased γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, loss of appetite, dark urine, itching, abdominal tenderness, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, fatigue, headache, taste disturbance, hearing loss, paresthesia, arthralgia, myalgia, olfactory disturbances, hypoglycemia, tinnitus, hearing impairment, purpuric rash, acute generalized exanthematous pustulosis (AGEP), muscle cramps, musculoskeletal rigidity, myopathy, elevated serum creatinine, elevated blood urea nitrogen, nephritis, injection site phlebitis, injection site pain, injection site inflammation, fever, asthenia, chest pain, chills, fatigue

This medication can be sensitive to air and moisture, so it must be stored in a sealed container. It is recommended to maintain storage temperatures between 1 and 30 degrees Celsius to preserve the medication's effectiveness and safety.

Appearance

Yellow oblong film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle