Combretum Tablets 5mg (Bisoprolol Fumarate)

Adult dose

Take without chewing with a drink in the morning on an empty stomach or during breakfast. 1. Hypertension, Angina As Bisoprolol Fumarate, take 5-10mg once daily. 5mg for mild cases, 10mg for severe cases; in specific cases, the maximum daily dose can be 20mg. Patients with severe renal or liver impairment should not exceed 10mg daily. 2. Stable Chronic Heart Failure Starting dose...

Child dose

There is no experience in using this medication for pediatric patients, so its administration is not recommended.

This medication should be used with caution in patients with certain heart diseases or severely impaired kidney and liver function due to insufficient experience with these cases. Patients with bronchial asthma or chronic obstructive pulmonary disease should take this medication alongside bronchodilators, as asthma symptoms may worsen. This medication may cause allergic reactions, and adrenaline treatment may not always be effective. Patients with psoriasis or a history of psoriasis should consider the risks and benefits of this medication carefully. Patients with certain hormone tumors should use this medication only after administering other drugs. This medication can mask symptoms of hyperthyroidism, so caution is advised for patients with thyroid disorders. Regular health status monitoring is required at the beginning of treatment, and sudden discontinuation can worsen heart conditions, so it should be tapered off gradually under medical supervision. This medication should not be used in patients with diabetic ketoacidosis, severe bradycardia, cardiogenic shock, right heart failure due to pulmonary hypertension, or acute heart failure. It should not be administered to pregnant women or those likely to become pregnant, as it may cause side effects in the fetus and newborn. If breastfeeding, it is advisable to avoid nursing while taking this medication, as it may be excreted in breast milk. Safety in pediatric patients has not been established, so it is not recommended for children. Elderly patients should start with a low dose and be carefully monitored, and dosage adjustment is necessary in cases of impaired kidney or liver function. This medication may affect driving or operating machinery, so caution is advised when starting treatment or changing doses, and alcohol should be avoided during use. In cases of overdose, symptoms such as severe bradycardia, hypotension, bronchospasm, worsening heart failure, and hypoglycemia may occur, requiring immediate medical attention. For long-term use, regular monitoring of heart function, blood pressure, and liver and kidney function is essential, and patients must inform their doctor about other medications they are taking due to potential interactions. Particular caution is needed when combining with calcium channel blockers, central nervous system medications, antiarrhythmics, and antidiabetic agents due to an increased risk of side effects. Before undergoing anesthesia, patients should inform healthcare providers that they are taking this medication and may need to taper it off gradually if necessary. This medication should be stored out of reach of children and kept in its original container to maintain its quality.

Serious side effects

Severe allergic reactions (hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor), severe skin reactions (severe rash accompanied by fever, blisters, peeling skin, oral/ocular mucosal pain), respiratory issues (shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever), liver abnormalities (jaundice, yellowing of the skin or eyes, severe drowsiness), severe neurological symptoms (sudden...

Mild side effects

• Bradycardia
• worsening heart failure
• coldness or numbness in limbs
• hypotension
• dizziness
• headache
• nausea
• vomiting
• diarrhea
• constipation

This medication should be stored in a tightly closed container to prevent air or moisture from entering. Additionally, it is best to store it at room temperature between 1°C and 30°C.

Appearance

A yellowish film-coated tablet shaped like a heart, with a scoreline on one side that is convex on both sides.

Package unit

30 tablets/bottle, 300 tablets/bottle, 500 tablets/bottle