Clarithromycin Tablet

Adult dosage

Adults: The usual dose of clarithromycin is 250mg (potency) per dose, twice daily; for severe infections, administer 500mg (potency) per dose, twice daily. The usual treatment duration is 7～14 days. In patients with renal failure and a creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) per dose twice daily. Do not administer this medicine to such patients for more than 14 days. Mycobacterial infections: Administer 500mg (potency) of this medicine per dose, twice daily. In this case, it should be administered in combination with other antimycobacterial agents, such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcer: Administer 500mg (potency) of this medicine 3 times daily with 40mg of omeprazole once daily for 14 days, followed by 40mg of omeprazole once daily for 14 consecutive days. In other words, administer clarithromycin 500mg (potency) per dose, 3 times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

Children 12 years and older: Same as adults. For children under 12 years, use clarithromycin dry syrup.

This medication should not be administered to certain patients. For example, patients who have allergies to the components in this medication or have had hypersensitivity reactions to certain antibiotics, as well as those with cardiac arrhythmias or severe liver impairment and severe kidney impairment, may be at risk if using this medication. Additionally, it is safe not to administer to pregnant or breastfeeding women and patients with central nervous system infections. Patients taking other medications that may interact with this drug should also avoid using it. There are also patients who need to use it with caution. Patients with impaired liver function, moderate or severe renal impairment, heart disease, the elderly, and those taking other antibiotics need to be particularly careful when using this medication. This drug can rarely cause serious allergic reactions, gastrointestinal disturbances, liver function abnormalities, kidney issues, skin rashes, neurological disturbances, and other various side effects, so if any abnormal symptoms occur during intake, it is essential to consult a healthcare professional immediately. Moreover, since this drug has a high potential for interactions with other medications, if patients are taking other medications, they must inform their healthcare provider, especially when taken with cardiac-related drugs, anticoagulants, certain antibiotics, and antiviral drugs. Pregnant or breastfeeding women should avoid this medication, and careful dosage adjustment and monitoring are necessary for children and the elderly. While taking this medication, continuous blood tests and liver and kidney function tests may be required, and in case of overdose, immediate emergency treatment should be received. Lastly, this medication should only be used for the minimum duration necessary for adequate infection treatment and should be taken as directed by healthcare providers to prevent the development of resistant bacteria.

Shock, anaphylactic symptoms, dyspnea, convulsions, flushing, rash, pruritus, urticaria, skin flushing, angioedema, joint swelling, drug eruption, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, malaise, flatulence, diarrhea, oral mucosal ulceration, upper abdominal pain, thirst, teeth discoloration, pancreatitis, increased amylase, taste disturbance, anorexia, constipation, stool discoloration, pseudomembranous colitis, hemorrhagic colitis, fever, cough, eosinophilia, eosinophilic lung infiltration, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, hepatic failure, fulminant hepatitis, increased AST, increased ALT, increased γ-GTP, increased LDH, increased ALP, elevated total bilirubin, elevated serum creatinine, increased BUN, interstitial nephritis, renal failure, rhabdomyolysis, stomatitis, oral mucositis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, taste disturbances, hearing loss, paresthesia, arthralgia, myalgia, olfactory disturbances, hypoglycemia, tinnitus, hearing impairment, purpuric rash, acute generalized exanthematous pustulosis, muscle spasms, musculoskeletal stiffness, myopathy, elevated serum creatinine, elevated serum urea, nephritis, injection site phlebitis, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased INR, prolonged prothrombin time, abnormal urine color, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, teeth discoloration, hyperhidrosis, papular rash, acne, Henoch-Schönlein purpura

This medication may be sensitive to air and moisture, so it should be stored in a sealed container. It is important to maintain the storage temperature between 1 degree and 30 degrees at room temperature. Storing it this way will safely preserve the drug's effectiveness.

Appearance

Yellow oblong film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle