Clarium Tablets (Clarithromycin)

Adult dose

Adults: The usual dose is 250mg (potency) of clarithromycin per dose twice daily; for severe infections, administer 500mg (potency) per dose twice daily. The usual treatment duration is 7～14 days. In patients with renal failure and creatinine clearance of 30mL/min or less, reduce the dose by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) per dose twice daily. Do not administer to these patients for more than 14 days. Mycobacterial infections: Administer 500mg (potency) of this drug per dose twice daily. In this case, it should be coadministered with other antimycobacterial drugs such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this drug 3 times daily for 14 days in combination with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Child dose

Children aged 12 years or older: Same as adults Children younger than 12 years: Use clarithromycin dry syrup.

This medication should not be used in certain patients. Patients with allergies to any of the ingredients in this medication or those who have had hypersensitivity reactions to certain classes of antibiotics should not take it. Furthermore, patients with specific heart diseases, liver impairment, or severely reduced kidney function should also avoid this medication. Pregnant or breastfeeding women should not take this medication. This medication should be used cautiously in patients with reduced liver or kidney function, those with heart disease, and elderly patients. Patients taking other antibiotics or multiple medications should also be careful when using this medication. Patients with drug allergies or a history of taking medications with similar ingredients should be especially cautious. When taking this medication, serious allergic reactions, skin rashes, gastrointestinal disturbances, respiratory issues, blood abnormalities, and neurological symptoms may occur, so if any symptoms appear, medical personnel should be alerted immediately. Regular testing may be required as it can affect liver and kidney function. This medication has many drug interactions, so if you are taking other medications, it is essential to inform your healthcare provider, particularly when taking drugs that affect the heart or drugs that are metabolized in the liver. Pregnant or breastfeeding women should not take this medication, and use in children may be restricted based on age. Elderly patients may need dose adjustments due to decreased body function, as the drug may remain in the body longer. In cases of overdose, gastrointestinal disturbances or psychiatric symptoms may occur, requiring immediate medical attention for appropriate treatment. This medication should be stored at room temperature away from direct sunlight, rather than being refrigerated, as it may be sensitive to air or moisture.

Shock, anaphylaxis symptoms, dyspnea, convulsions, flushing, rash, itching, urticaria, skin erythema, angioedema, joint swelling, drug eruption, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, malaise, flatulence, diarrhea, oral mucosal erosion, epigastric pain, thirst, tooth discoloration, pancreatitis, increased amylase, dysgeusia, anorexia, constipation, stool discoloration, pseudomembranous colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic lung infiltration, interstitial pneumonia, chronic bronchitis, exacerbation of acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzyme levels, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, increased γ-GTP, elevated LDH, increased ALP, elevated total bilirubin, increased serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, atrial fibrillation, ECG QT prolongation, premature contractions, palpitations, cardiac arrest, vasodilation, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, hyperhidrosis, papular rash, acne, Henoch-Schonlein purpura, acute generalized pustular eruptions, muscle cramps, musculoskeletal rigidity, myalgia, myopathy, elevated serum creatinine, increased blood urea, nephritis, injection site phlebitis, injection site pain, injection site inflammation, lethargy, fever, asthenia, chest pain, chills, fatigue, abnormal albumin/globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased INR, prolonged prothrombin time, urine discoloration, psychotic disorder, state of confusion, abnormal dreams, headache, loss of consciousness, movement disorders, non-vestibular dizziness, drowsiness, tremor, vestibular dizziness, hearing impairment, hearing loss, hypoglycemia

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is best to maintain a storage temperature between 1 to 30 degrees Celsius at room temperature to safely preserve its efficacy.

Appearance

Oval, yellow film-coated tablet with a vanilla flavor

Package unit

30 tablets, 200 tablets (bottle)