Crabix Tablet (Clarithromycin)

Adult dose

Adults: The usual dose of clarithromycin is 250mg (potency) twice a day. For severe infections, administer 500mg (potency) twice a day. The treatment period is usually 7～14 days. In patients with renal impairment and a creatinine clearance of 30mL/min or less, the dose should be reduced by half. That is, administer 250mg (potency) once a day, or 250mg (potency) twice a day for severe infections. Do not administer for more than 14 days in these patients. Mycobacterial infections: Administer 500mg (potency) of this medicine twice a day. In this case, it must be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this medicine 3 times a day in combination with omeprazole 40mg once a day for 14 days, followed by omeprazole 40mg once a day for 14 consecutive days. That is, administer clarithromycin 500mg (potency) 3 times a day for 14 days (days 1～14), and omeprazole 40mg once a day for 28 days (days 1～28).

Child dose

Children 12 years and older: Same as adults. For children under 12 years, use clarithromycin dry syrup.

This medication should not be used in patients who are allergic to certain components. Patients who have had hypersensitivity reactions to drugs of a similar class should also avoid administering this medication. Furthermore, it is safest for patients with heart-related diseases or severely impaired liver and kidney function not to use this medication. Severe side effects such as cardiac arrhythmias may occur in conjunction with certain drugs, so if you are currently taking other medications, you must inform your doctor or pharmacist. Women who are pregnant or breastfeeding should not take this medication, and it should be used with caution in children and older adults. This medication can cause various adverse reactions such as gastrointestinal disorders, allergic reactions, liver dysfunction, and kidney dysfunction; if symptoms appear, you should consult a healthcare professional immediately. To prevent antibiotic resistance, it is important to take this medication only for the necessary duration and not to stop taking it arbitrarily even if symptoms improve. Because there is a high chance of interactions with other medications, you should inform healthcare providers of all medications you are taking, especially if you have heart disease, liver, or kidney conditions. Overdosing may lead to gastrointestinal disorders or psychiatric symptoms, so the prescribed dosage must be strictly followed, and if any abnormal symptoms occur, immediate medical attention should be sought. While taking this medication, you may experience dizziness or confusion when driving or operating machinery, so caution is needed. Regular blood tests and liver and kidney function tests are recommended to check for abnormalities.

Shock, anaphylactic symptoms, dyspnea, convulsions, flushing, rashes, itching, urticaria, mild skin flushing, angioedema, joint swelling, drug eruption, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, discomfort, gas retention, diarrhea, oral mucosal erosion, upper abdominal pain, thirst, transient tooth discoloration, pancreatitis, increased amylase, dysgeusia, anorexia, constipation, stool discoloration, pseudomembranous colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic lung infiltrates, interstitial pneumonia, chronic bronchitis, acute exacerbation of acute maxillary sinusitis, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, ageusia, hyposmia, anxiety, insomnia, nightmares, tinnitus, confusion, orientation disturbance, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzyme levels, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, stomatitis, oral mucositis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, fatigue, headache, dysgeusia, hearing loss, paraesthesia, arthralgia, myalgia, olfactory disturbances, hypoglycemia, tinnitus, hearing impairment, purpuric rash, acute generalized exanthematous pustulosis (AGEP), muscle spasms, musculoskeletal rigidity, myopathy, elevated blood urea, nephritis, phlebitis at injection site, injection site pain, injection site inflammation, fever, asthenia, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated alkaline phosphatase in the blood, elevated lactate dehydrogenase in the blood, increased international normalized ratio, prolonged prothrombin time, abnormal urine color, soft tissue infection, candidiasis, gastroenteritis, infection, vaginitis, leukopenia, neutropenia, thrombocytosis, agranulocytosis, thrombocytopenia, anaphylactic reaction, angioedema, decreased appetite, insomnia, nervous hyperactivity, sound distortion, psychogenic disorder, confusion state, abnormal dreams, movement dysregulation, non-vestibular dizziness, drowsiness, tremor, vestibular dizziness, hearing impairment, cardiac arrest, atrial fibrillation, premature contractions, palpitations, vasodilation, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating

This medication should be stored away from direct sunlight and in a cool place, specifically at room temperature between 1°C and 30°C. It is also important to keep it in a sealed container to prevent air from entering.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle