Medication info
Zobatin Tablet 20 mg (Simvastatin)

Zobatin Tablet 20 mg (Simvastatin)

Prescription medicationTablet경구
Ingredient · strength
Simvastatin›20mg / 1 tablet
Manufacturer / importer
진양제약(주)
Appearance
Brownish yellow oval film-coated tablet
Packaging
(Domestic) 30 tablets/bottle, 100 tablets/bottle (Export) 30 tablets (10 tablets x 3 PTP)
Approval status
Active

MFDS item code 200401411 · Notified 2004.01.28 · Insurance code 650301130

Summary

Main use
Reduction of the risk of cardiovascular diseases and improvement of hyperlipidemia
Who takes it
Adults · Children
Adult dose
1. Adult patients at high risk for cardiovascular disease: Administer 40 mg of Simvastatin daily. 2. Adult patients with hyperlipidemia: The usual starting dose is 20 mg once daily in the evening. Mild to moderate patients may start with 10 mg. 3. General dosage range: Administer 5-40 mg once daily in the evening and adjust the dosage based on treatment goals and patient response. 4. Patients with homozygous familial hypercholesterolemia: 1 daily.
Child dose
For children with heterozygous familial hypercholesterolemia (ages 10-17): Administer 10 mg once daily in the evening. Recommended dosage range is 10-40 mg per day with a maximum dose of 40 mg.

Ingredients

Manufacturer
진양제약(주)

Efficacy & effects

Reduction of the risk of cardiovascular diseases and improvement of hyperlipidemia

  • Coronary heart disease
  • diabetes
  • peripheral vascular disease
  • stroke
  • hypercholesterolemia
  • dyslipidemia
  • abnormal beta-lipoproteinemia
  • hypertriglyceridemia
  • familial hypercholesterolemia
View approved original text

This medication is effective in reducing the risk of cardiovascular diseases. It lowers the risk of mortality from heart disease and events such as myocardial infarction and stroke in adult patients with a history of coronary heart disease, diabetes, peripheral vascular disease, or stroke. Additionally, it reduces the risk of complications after vascular surgeries. In hyperlipidemia patients, it decreases total cholesterol and bad LDL cholesterol levels while increasing good HDL cholesterol levels, thereby improving blood lipid concentrations. It is particularly used as an adjunctive treatment for familial hypercholesterolemia or mixed dyslipidemia and can be applied to children with familial hypercholesterolemia. This medication is used to maintain cardiovascular health and reduce the risk of cardiovascular diseases.

How to take

Adult dose

1. Adult patients at high risk for cardiovascular disease: Administer 40 mg of Simvastatin daily. 2. Adult patients with hyperlipidemia: The usual starting dose is 20 mg once daily in the evening. Mild to moderate patients may start with 10 mg. 3. General dosage range: Administer 5-40 mg once daily in the evening and adjust the dosage based on treatment goals and patient response. 4. Patients with homozygous familial hypercholesterolemia: 1 daily.

Child dose

For children with heterozygous familial hypercholesterolemia (ages 10-17): Administer 10 mg once daily in the evening. Recommended dosage range is 10-40 mg per day with a maximum dose of 40 mg.

Precautions

This medication can have side effects that affect muscles; therefore, if symptoms like muscle pain or weakness occur, notify your doctor immediately. Patients taking high doses of this medication are at increased risk for myopathy or rhabdomyolysis, so caution is necessary. This medication may affect liver function, so it should not be taken by patients with liver disease or abnormally high liver function test results. Women who are pregnant or may become pregnant, as well as nursing women, should not take this medication. The risk of muscle-related side effects may increase when this medication is taken with certain drugs, so consult your doctor or pharmacist if you are on other medications. Elderly patients, women, and those with kidney or thyroid dysfunction should exercise particular caution when taking this medication. Regular liver function tests and muscle-related tests are recommended, and if any abnormal symptoms occur, consult a healthcare provider immediately. This medication may interact with certain foods, such as grapefruit juice, so it is advisable to avoid grapefruit juice while taking it. It is not recommended for children or patients under the age of 10, and in children over 10 years of age, it should be taken according to a doctor's advice. In the event of overdose, contact a healthcare provider immediately for appropriate treatment. This medication should be stored in its original container and kept out of reach of children.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/conjunctival mucosa, breathlessness or difficulty breathing, asthma attacks, coughing with fever accompanied by respiratory abnormalities, yellowing of skin or eyes (jaundice), extreme fatigue, sudden and severe headaches, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urinary issues.

Mild side effects

  • Abdominal pain
  • weakness
  • constipation
  • diarrhea
  • dyspepsia
  • bloating
  • nausea
  • headache
  • upper respiratory infection
  • atrial fibrillation
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  • gastritis
  • insomnia
  • dizziness
  • bronchitis
  • sinusitis
  • eczema
  • urinary tract infection
  • muscle pain
  • muscle cramps
  • joint pain
  • taste disturbances
  • extraocular muscle disorders
  • facial palsy
  • tremor
  • sensory disturbances
  • peripheral neuropathy
  • peripheral nerve paralysis
  • psychiatric disorders
  • anxiety
  • sleep disorders
  • depression
  • cataract progression
  • ocular muscle paralysis
  • anemia
  • alopecia
  • itching
  • multiple.

Not everyone experiences these, and they can vary from person to person.

Storage

Store this medication in a tightly sealed container to protect it from air and moisture. Furthermore, to maintain the medication's effectiveness, it is important to store it at room temperature between 1 degree and 30 degrees.

Appearance and packaging

Appearance

Brownish yellow oval film-coated tablet

Package unit

(Domestic) 30 tablets/bottle, 100 tablets/bottle (Export) 30 tablets (10 tablets x 3 PTP)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.