Cardiron Tablet (Carvedilol)

Adult dose

Do not increase the dose or stop taking this medicine without a doctor's instruction. 1. Essential hypertension 1) Adults (1) For the first 2 days, administer carvedilol 12.5 mg orally once daily, then administer 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If an increase is needed, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. 2) Elderly patients Some elderly patients may respond adequately to 12.5 mg once daily. If the effect is insufficient after 2 weeks of treatment, the dose may be increased. 2. Chronic stable angina 1) For the first 2 days, administer 12.5 mg of this medicine orally twice daily, then administer 25 mg orally twice daily. 2) The usual dose is 25 mg twice daily for 2 weeks. If an increase is needed (excluding elderly patients), the dose may be increased to 50 mg twice daily. 3. Congestive heart failure Before starting treatment with this medicine, the patient's existing standard treatment regimen should be stable (conventional treatment for chronic heart failure with an ACE inhibitor, a diuretic, and usually a digitalis preparation). Fluid retention should also be minimized before starting treatment with this medicine. 1) In general, the initial dose is 3.125 mg of this medicine orally twice daily for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg twice daily for 2 weeks, then to 12.5 mg twice daily for 2 weeks, and then to 25 mg twice daily. 2) Increase the dose gradually after taking each dose level for at least 2 weeks, up to the dose tolerated by the patient. 3) The minimum effective dose is 6.25 mg twice daily. The maximum dose is 25 mg twice daily for patients weighing 85 kg or less and 50 mg twice daily for patients weighing more than 85 kg. 4) To control the rate of absorption, administration with meals in the morning and evening is recommended. Taking this medicine with meals slows the rate of absorption and may reduce the incidence of orthostatic hypotension.

This medication should not be used by certain patients. For example, patients with allergic reactions to this drug or its components, those in cardiogenic shock, patients with severe cardiac conduction disorders, patients with cor pulmonale, those with diabetic ketoacidosis, patients with severely impaired cardiac function, patients with asthma or chronic obstructive pulmonary disease, those with secondary hypertension, certain cardiac disorders, patients with severe liver function impairment, pregnant or nursing women, and patients with peripheral vascular diseases should not take this medication. Additionally, patients with diabetes, those with a history of allergies, patients with impaired kidney function, elderly patients, and those with low blood pressure should be particularly cautious when using this medication and must be closely monitored according to a physician's instructions. During treatment with this medication, symptoms such as dizziness, headache, fatigue, and in severe cases, hallucinations or mental disorders may occur, as well as a slow heart rate or a sudden drop in blood pressure. If any symptoms appear, immediate consultation with healthcare professionals is recommended. Regular cardiac function tests, blood pressure, and electrocardiogram checks should be performed, and abrupt discontinuation of the medication can worsen cardiac problems, thus it is essential to gradually reduce the dosage under a physician's guidance. This medication may interact with other drugs, so if other medications are being taken, it is crucial to inform healthcare professionals, especially if taken in conjunction with antihypertensives, antidiabetics, antidepressants, sedatives, anesthetics, or alcohol. Pregnant or nursing women should not take this medication, and safety for children and adolescents has not been established, thus use is not recommended. In the elderly, due to decreased liver function, drug concentration may increase, thus starting with a lower dosage and monitoring closely is advised. In case of overdose, severe hypotension, decreased heart rate, impaired cardiac function, shock, and respiratory distress may occur, necessitating immediate medical attention for appropriate treatment. This medication may discolor if exposed to light, thus it should be stored in an opaque container and kept out of reach of children.

• Dizziness
• headache
• fatigue
• weakness
• hallucinations
• confusion
• depression
• sleep disorders
• nightmares
• psychosis

This medication is sensitive to light and must be stored in a container that does not allow light exposure. Additionally, it is best to store the medication at room temperature, specifically between 1°C and 30°C. Storing it this way will help maintain the effectiveness of the medication.

Appearance

White round tablet

Package unit

100 tablets - 10 tablets/pack [X 10]