Daewoong Itraconazole Capsule (Itraconazole Solid Dispersion)

Adult dosage

To increase absorption, this medicine should preferably be taken immediately after a meal. 1. Short-term treatment 1) Candidal vaginitis: Administer itraconazole 200 mg per dose 2 times daily (morning and evening) for 1 day, or 200 mg once daily for 3 days. 2) Tinea versicolor: Administer 200 mg once daily for 7 days. 3) Tinea corporis and tinea cruris (jock itch): Administer 100 mg once daily for 15 days. 4) Tinea manuum (interdigital type) and tinea pedis (interdigital type): Administer 100 mg once daily for 15 days. 5) Tinea manuum (palms) and tinea pedis (soles): Administer 100 mg once daily for 30 days, or 200 mg per dose 2 times daily for 7 days. 6) Oral candidiasis: Administer 100 mg once daily for 15 days. 7) Fungal keratitis: Administer 200 mg once daily for 21 days. 2. Onychomycosis 1) Pulse therapy Administer 200 mg per dose 2 times daily for 1 week, followed by a 3-week drug-free interval; this constitutes one cycle. Administer up to 2 cycles for infection of the fingernails only and up to 3 cycles for infection of the toenails. 2) Continuous therapy Administer 200 mg once daily for 3 months. 3. Systemic fungal infections In patients with impaired immune function, such as those with neutropenia, AIDS, or organ transplant recipients, the oral bioavailability of this medicine may be reduced; therefore, if necessary, increase the dose twofold. Aspergillosis: 200 mg once daily; average treatment duration 2–5 months. For invasive or disseminated disease, increase to 200 mg per dose 2 times daily. Candidiasis: 100–200 mg once daily; average treatment duration 3 weeks–7 months. Cryptococcal meningitis: 200 mg 2 times daily; average treatment duration 2 months–1 year. Maintenance therapy: 200 mg once daily. Paracoccidioidomycosis: 100 mg once daily; average treatment duration 6 months

This medication should not be used in patients with compromised heart function or a history of heart failure. If symptoms of heart failure occur during treatment, use should be discontinued immediately. Patients with allergies to this medication or its components, those with reduced heart function, and those taking certain drugs concurrently should avoid use. Caution is especially warranted due to the potential for significant drug interactions. Women who are pregnant, may become pregnant, or are nursing should not use this medication. Patients with impaired liver function or a history of liver toxicity should use this medication with caution and have regular liver function tests. Patients with reduced kidney function may also require dosage adjustments when using this medication. Patients with weakened immune systems, such as those with AIDS or organ transplant recipients, may require dosage adjustments due to lower absorption rates of this medication. This medication can cause gastrointestinal symptoms such as headache, nausea, abdominal pain, as well as skin reactions like itching and rash. Rarely, serious side effects may include liver dysfunction, heart issues, and neurological problems; thus, if any unusual symptoms occur, consult a physician immediately. This medication has many potential interactions with other drugs, and caution should be exercised during combined use. Specifically, consult a healthcare professional if using with drugs that may affect the heart or are metabolized in the liver. There may be dizziness or visual disturbances when driving or operating machinery, so caution is advised. This medication is not recommended for pregnant or breastfeeding women, and women of childbearing age should take appropriate contraceptive measures after using this medication. Use with caution in children or the elderly, and dose adjustments may be necessary based on individual conditions. In the case of overdose, there is no specific antidote, so seek immediate medical attention for appropriate treatment. This medication should be stored out of reach of children and kept in its original container to maintain quality.

Headache, nausea, abdominal pain, rhinitis, sinusitis, upper respiratory tract infection, leukopenia, hypersensitivity, taste disorder, sensory impairment, sensory abnormality, tinnitus, constipation, diarrhea, dyspepsia, bloating, vomiting, liver dysfunction, hyperbilirubinemia, itching, rash, urticaria, pollakiuria, erectile dysfunction, menstrual disorders, edema, granulocytopenia, thrombocytopenia, anaphylactoid reaction, hyperglycemia, hyperkalemia, hypokalemia, hypomagnesemia, confusion, peripheral neuropathy, dizziness, drowsiness, trembling, heart failure, left ventricular failure, tachycardia, hypertension, hypotension, pulmonary edema, speech disorders, cough, gastrointestinal disorders, liver failure, hepatitis, jaundice, erythematous rash, hyperhidrosis, myalgia, arthralgia, kidney disorders, urinary incontinence, generalized edema, facial edema, chest pain, fever, pain, fatigue, chills, leukocytosis, eosinophilia, anemia, vascular edema, serum sickness, angioneurotic edema, anaphylaxis, anaphylactic shock, allergic reaction, diplopia, visual impairment, transient hearing loss, permanent hearing loss, ventricular premature contraction, atrial block, palpitations, increased bowel motility, belching, glossitis, stomatitis, abdominal and lower back pain, pancreatitis, increased serum total protein, increased total bilirubin, increased LAP, anorexia, malaise, brown urine, erythema multiforme, hair loss, photosensitivity reaction, exfoliative dermatitis, leukocytoclastic vasculitis, acute generalized exanthematous pustulosis, increased BUN, positive urinary protein, positive urinary glucose, decreased libido, drowsiness, shoulder stiffness, insomnia, chest pain, elevated serum triglycerides, flushing, elevated serum uric acid, elevated serum potassium, serum sickness, angioneurotic edema, anaphylactic reaction, hypertriglyceridemia, trembling, blurred vision, congestive heart failure, dyspnea, severe hepatotoxicity, toxic epidermal necrolysis, Stevens-Johnson syndrome, acute generalized exanthematous pustulosis, exfoliative dermatitis, increased serum creatine phosphokinase

Store this medication at room temperature between 1°C and 30°C, and it is important to keep it in a tightly sealed container to prevent air exposure. This will help maintain the medication's effectiveness and prevent degradation.

Appearance

An orange hard capsule with a beige upper part containing grayish-white granules in the lower part.

Package unit

Company packaging unit