Vasotrol Tablet 12.5mg (Carvedilol)

Adult dose

Do not increase the dose or discontinue use without a physician's instructions. 1. Essential hypertension 1) Adults (1) Administer carvedilol 12.5mg orally once daily for the first 2 days, then administer 25 mg orally once daily. (2) Usually, administer 25mg orally once daily for 2 weeks. If an increase is needed, increase to 25mg twice daily. The maximum dose per administration is 25mg, and the maximum daily dose is 50mg. 2) Elderly patients In some elderly patients, 12.5mg once daily may provide an adequate effect. However, the dose may be increased if the effect is insufficient after 2 weeks of treatment. 2. Chronic stable angina 1) Administer this medicine 12.5mg per dose twice daily orally for the first 2 days, then administer 25mg per dose twice daily orally. 2) Usually, administer 25mg per dose twice daily for 2 weeks. If an increase is needed (excluding elderly patients), the dose may be increased to 50mg per dose twice daily. 3. Congestive heart failure Before starting treatment with this medicine, the standard treatment regimen already being administered (conventional treatment for chronic heart failure with an ACE inhibitor, a diuretic, and usually a digitalis preparation) must be stable. Fluid retention should also be minimized before starting treatment with this medicine. 1) In general, for initial treatment, administer this medicine 3.125mg per dose twice daily orally for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25mg per dose twice daily for 2 weeks, then increase to 12.5mg per dose twice daily for 2 weeks, and then increase to 25mg per dose twice daily. 2) Increase the dose gradually after taking each dose for at least 2 weeks, up to the dose tolerated by the patient. 3) The minimum effective dose is 6.25mg per dose twice daily. The maximum dose is 25mg per dose twice daily for patients weighing 85kg or less, and 50mg per dose twice daily for patients weighing more than 85kg. 4) To control the rate of absorption, it is recommended to take this medicine with meals in the morning and evening. Taking it with meals slows the rate of absorption and may reduce the incidence of postural hypotension.

This medication should not be used in certain patients. For example, it should not be administered to patients with allergy to this medication or its components, very weak cardiac function, excessively slow heart rate, problems with heart conduction, or pulmonary-related heart diseases. Additionally, it may pose risks for patients with cardiac issues associated with diabetes or respiratory diseases such as asthma or chronic obstructive pulmonary disease. Pregnant or nursing women should also avoid taking this medication, as well as patients with genetic lactose intolerance. Special caution should be taken when administering this medication to patients with diabetes, severe allergic reactions, weakened heart or kidney function, and the elderly. During use, symptoms such as dizziness, headache, and fatigue may occur, and heart rate may slow down, or blood pressure may drop excessively; therefore, regular checks of heart function and blood pressure are necessary. Furthermore, it is essential to monitor liver or kidney function as it may worsen. This medication can interact with other drugs, so patients taking other medications must inform their healthcare provider. Caution is especially needed when taken with antihypertensives, diabetes medications, cardiac medications, sedatives, etc. Pregnant or lactating women should avoid taking this medication due to potential effects on the fetus or newborn. The safety of this medication for children or adolescents under 18 has not been confirmed, so it is best not to use it. Elderly patients may have reduced liver function, so they should start at a lower dosage and be closely monitored. In case of overdose, severe cardiac problems, breathing difficulties, and loss of consciousness may occur, and immediate medical attention is necessary. This medication may worsen heart-related symptoms if suddenly discontinued, so it should be tapered off according to medical advice. Patients should avoid driving or operating dangerous machinery while taking this medication and should also be cautious with alcohol intake. As this medication can degrade when exposed to light, it should be stored in a dark container that protects it from direct sunlight and kept out of reach of children.

• Dizziness
• headache
• fatigue
• weakness
• hallucinations
• confusion
• depression
• sleep disorders
• nightmares
• psychosis

This medication is sensitive to light, so it should be stored in a light-resistant container. Additionally, the medication should be kept at room temperature between 1°C and 30°C. This way, the effectiveness and safety of the medication can be maintained.

Appearance

The tablet is round and reddish-brown.

Package unit

100 tablets/PTP