Ceclarin Tablets (Clarithromycin)

Adult dose

Adults: Clarithromycin is usually administered at 250mg (potency) per dose twice daily. For severe infections, administer 500mg (potency) per dose twice daily. The usual treatment duration is 7～14 days. In patients with renal failure and creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) per dose twice daily. Do not administer to these patients for more than 14 days. Mycobacterial infections: Administer 500mg (potency) of this drug per dose twice daily. In this case, it should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this drug 3 times daily in combination with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (Days 1～14), and omeprazole 40mg once daily for 28 days (Days 1～28).

Child dose

Children aged 12 years and older: Same as adults For children under 12 years of age, use clarithromycin dry syrup.

This medication should not be administered to certain patients. For example, patients allergic to any component contained in this medication, those who have had hypersensitivity reactions to specific antibiotics, and patients with cardiac rhythm abnormalities, severe liver dysfunction, or severe renal impairment should not use it. Moreover, it should not be given to patients taking specific medications, pregnant or lactating women, or patients with central nervous system infections, nor should it be used in patients with lactose intolerance due to its lactose content. Patients with impaired liver or kidney function, those with heart disease, elderly patients, and patients currently taking other antibiotics should exercise particular caution when using this medication. Such patients have a higher risk of side effects and should consult with healthcare professionals before taking the medication. This medication can rarely cause severe allergic reactions, gastrointestinal disturbances, liver dysfunction, renal problems, skin rashes, and various central nervous system symptoms. If any abnormal symptoms appear, the medication should be stopped immediately and a doctor consulted. Additionally, this medication may interact with other drugs, so if patients are currently taking any other medications, they must inform their healthcare professional. Caution is particularly needed when taken with drugs that affect cardiac rhythm, drugs metabolized in the liver, hypoglycemics, anticoagulants, and certain antiviral medications. It is safer for pregnant or breastfeeding women not to take this medication, and for children and the elderly, consultation with a professional is essential before use. In case of overdose, gastrointestinal disturbances or neurological symptoms may occur, so compliance with the prescribed dosage is crucial, and in the event of overdose, immediate medical attention should be sought. Long-term or repeated use of this medication may lead to the development of resistant bacteria, so it is important to confirm the susceptibility of the infectious bacteria and use it only for the necessary duration. Finally, this medication may require caution when driving or operating machinery, so if dizziness or confusion occurs during treatment, such activities should be avoided.

Shock, anaphylactic symptoms, dyspnea, convulsions, erythema, rash, pruritus, urticaria, skin erythema, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, malaise, gas retention, diarrhea, oral mucosal ulceration, upper abdominal pain, dry mouth, tooth discoloration, pancreatitis, increased amylase, dysgeusia, anorexia, constipation, fecal discoloration, membranous colitis, hemorrhagic colitis, fever, cough, eosinophilia, eosinophilic lung infiltrates, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremor, paresthesia, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash with eosinophilia and systemic symptoms, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, taste disorder, hearing loss, dysesthesia, arthralgia, myalgia, olfactory disturbance, tinnitus, hearing impairment, hypoglycemia, purpuric rash, acute generalized pustular psoriasis, vasodilation, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, tooth discoloration, abnormal liver function tests, increased alanine aminotransferase, increased aspartate aminotransferase, increased gamma-glutamyltransferase, hepatocellular jaundice, vesicular dermatitis, hyperhidrosis, papular rash, acne, Henoch-Schonlein purpura, muscle cramps, musculoskeletal stiffness, myopathy, elevated blood urea nitrogen, injection site phlebitis, injection site pain, injection site inflammation, fever, asthenia, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated alkaline phosphatase, elevated lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, abnormal urine color

This medication may be sensitive to air or moisture, so it should be stored in a sealed container. It is advisable to maintain a storage temperature in the range of 1 to 30 degrees Celsius. Storing it this way can help preserve its effectiveness and safety over a long period.

Appearance

Yellow, round, film-coated tablet with a vanilla flavor

Package unit

30 tablets/bottle