B Braun Hartmann Solution

Adult administration

Usually, 500 to 1,000 mL is administered by slow intravenous infusion to adults. The administration rate is 300 to 500 mL per hour (75 to 120 drops per minute). The dosage and administration rate should be adjusted appropriately based on age, weight, and symptoms.

This medication is a calcium-containing solution administered intravenously. When using this medication, it is essential to administer it separately from the antibiotic Ceftriaxone when using the same infusion apparatus, as Ceftriaxone and calcium can precipitate and be dangerous. Allergic reactions may occur during administration, so if symptoms such as hives, rash, or difficulty breathing appear, immediately stop the administration and seek appropriate treatment. Due to the high potassium content, there is a risk of elevated potassium levels in the blood; therefore, patients with poor kidney function, dehydration, or cardiac conditions should be particularly cautious and may need to check serum potassium levels frequently. It may also increase sodium and chloride levels, so patients with hypertension, congestive heart failure, or liver disease should use this medication cautiously to avoid fluid overload or electrolyte imbalance, with regular blood tests and kidney function evaluations. Additionally, this medication can cause hyponatremia, so at-risk groups such as children, the elderly, postoperative patients, and patients with mental disorders should be closely monitored for symptoms and have serum sodium levels monitored. Patients with high calcium levels or a history of calcium kidney stones should avoid administration of this medication. Rapid or excessive administration of this medication can lead to side effects such as cerebral edema, pulmonary edema, and peripheral edema, so the administration rate and dosage must be adjusted. This medication should be used with caution in patients with diminished kidney function, heart failure, dehydration, severely impaired liver function, and urinary obstruction. During pregnancy, it should only be used when necessary after considering the risks to the fetus, and care should be taken when administering to children or newborns due to the higher risk of hyponatremia and brain damage. This medication may interact with various other drugs, so particularly when used with drugs that cause hyperkalemia, lithium, digoxin, diuretics, anticonvulsants, corticosteroids, etc., consultation with a healthcare professional is recommended, and blood tests should be performed to monitor the condition. Before administration, disinfect the skin and equipment to prevent infection, and warm the solution to body temperature before use; any remaining solution should be disposed of immediately after opening. Administer the solution slowly intravenously to reduce the risk of adverse effects. Finally, this medication should be stored at room temperature and must be administered strictly according to healthcare provider instructions.

Serious side effects

• Hives
• anaphylaxis (severe allergic reaction)
• difficulty breathing
• peripheral edema
• pulmonary edema
• cerebral edema
• cardiac arrest

Mild side effects

• Vomiting
• hypertension
• tachycardia
• chills
• fever
• generalized papules and erythema
• rash
• hyponatremia
• hypernatremia
• hyperchloremic acidosis

This medication should be stored in a sealed container to prevent air ingress. It is also advisable to keep it away from direct sunlight and store it at room temperature.

Appearance

A colorless injectable solution filled in a polyethylene container

Package unit

Bottle - 500 milliliters/bottle, Bottle - 1000 milliliters/bottle