Porison Injection (Ceftriaxone Sodium Hydrate)

Adult administration

Adults and children over 12 years: Administer 1-2 g (active ingredient) of ceftriaxone once daily by intravenous or intramuscular injection. For infections caused by severe diseases or moderately sensitive pathogens, the dose may be increased to 4 g (active ingredient) once daily. For treating gonorrhea, a single intramuscular injection of 250 mg (active ingredient) is recommended. For the prevention of infections before and after surgery: Administer 1-2 g (active ingredient) once, 30-90 minutes prior to surgery.

Child administration

Neonates (within 14 days of birth): Administer 20-50 mg (active ingredient) per Kg of body weight, once daily, without exceeding 50 mg (active ingredient) per Kg of body weight. Administered regardless of whether the child is premature or full-term. Infants and children...

This medication should not be mixed with solutions containing calcium or other drugs. In particular, it must never be administered with calcium in neonates, as this can result in precipitation, posing a fatal risk. Patients who are allergic to this medication or have a hypersensitivity reaction to cephalosporin or penicillin antibiotics should not use it. Additionally, premature infants or neonates with jaundice or hypoalbuminemia may be at risk if this medication is used. When using this medication, it should be administered with caution to individuals with a history of drug allergies or those who frequently exhibit allergic symptoms such as bronchial asthma and rashes. Patients with impaired kidney function may require dosage adjustments due to potentially increased drug concentrations. If symptoms like rash, hives, difficulty breathing, dizziness, or vomiting occur while using this medication, it should be stopped immediately and medical attention sought. Long-term or high-dose use may result in adverse reactions in multiple organs including the liver, kidneys, and blood, thus requiring regular examinations. This medication should be used with caution in pregnant or nursing women, considering the potential effects on the fetus or neonate. Caution is advised when driving or operating machinery since side effects like dizziness may occur. Always check for possible drug interactions when administering this medication, especially ensure that it is never administered simultaneously with calcium-containing solutions. For storage, the prepared solution should be used as soon as possible; it is safe for up to 6 hours at room temperature and within 24 hours when refrigerated.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, high fever accompanied by severe rash, blistering, skin peeling, oral/ocular mucosal pain, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by coughing and fever, jaundice (yellowing of the skin or eyes), feeling extremely fatigued, sudden and severe headaches, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination issues.

Mild side effects

• Eosinophilia
• leukopenia
• thrombocytopenia
• diarrhea
• rash
• increased liver enzymes
• headache
• dizziness
• bronchospasm
• loose stools

This medication should be stored in a sealed container to protect it from air and moisture. The storage temperature should ideally be maintained at room temperature between 1°C and 30°C. Proper storage ensures the effectiveness of the drug is maintained.

Appearance

[Method 1 for domestic use] A colorless and transparent vial filled with white to light yellow crystalline powder. [Method 2 for export] A transparent vial containing white to light yellow powder injection. [Method 3 for export] White to light yellow...

Package unit

1 vial, 10 vials