Leflocin Tablet (Levofloxacin Dihydrate)

Adult dose

Typically, adults should take 100 mg of levofloxacin orally 2 to 3 times a day. Patients with severe infections or insufficient response should take 200 mg orally 3 times a day. Adjustments may be made according to age and symptoms.

This drug is a fluoroquinolone antibiotic and may cause severe side effects such as tendinitis, tendon rupture, peripheral neuropathy, central nervous system abnormalities, and exacerbation of myasthenia gravis. If these abnormal reactions occur, the use of this medication should be discontinued immediately, and it should not be administered to patients with myasthenia gravis. The risk of tendon rupture is particularly high in elderly patients, those with impaired renal function, those receiving high doses, and those co-administered with corticosteroids, so co-administration should be avoided. Moreover, this drug may increase the risk of seizures; thus, caution is required in patients with a history of epilepsy or seizures, and if seizures occur, the medication should be stopped immediately. It should not be given to patients with hypersensitivity to this drug or a history of tendinitis or tendon rupture from this or similar drugs, growing children and adolescents, women who are pregnant or breastfeeding, and patients with epilepsy. Patients with severe renal impairment, central nervous system disorders, elderly patients, and those with diabetes require special attention during administration, and blood glucose control and renal function should be closely monitored. This drug may cause various side effects including serious allergic reactions, liver dysfunction, blood disorders, gastrointestinal issues, musculoskeletal problems, and skin diseases; therefore, if unusual symptoms occur, medical consultation should be sought immediately. Additionally, this drug may interact with other medications, so caution is needed when taken with non-steroidal anti-inflammatory drugs, anticoagulants, antacids, and hypoglycemic agents. Women who are pregnant or breastfeeding should not use this drug, and it should not be administered to growing children and adolescents. Elderly patients may experience increased drug concentration due to decreased renal function, making dose adjustment and monitoring for side effects crucial. In case of overdose, central nervous system symptoms and cardiac abnormalities may arise, requiring immediate medical treatment. Long-term use of this medication may lead to the development of resistant bacteria; therefore, it is advisable to administer it at the minimum effective dose only for the necessary duration. Finally, during the use of this medication, strong sunlight or exposure to artificial ultraviolet light should be avoided, and caution should be exercised when driving or operating machinery if dizziness or drowsiness occurs.

Serious side effects

Hives, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweats, pallor, severe rash with high fever, blisters, pain in the mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, cough with fever-associated respiratory issues, yellowing of the skin or eyes (jaundice), extreme fatigue, sudden and severe headaches, lightning headaches, seizures, altered consciousness, visual disturbances, paralysis, urination issues.

Mild side effects

• Insomnia
• dizziness
• headache
• tremors
• anxiety
• depression
• hallucinations
• paranoia
• nervousness
• delirium

This medication should be stored in a tightly sealed container to prevent air or moisture from entering, and it is recommended to keep it at room temperature between 1 degree and 30 degrees Celsius. Proper storage will help maintain the drug's efficacy and prevent deterioration.

Appearance

White or light yellow round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle, 500 tablets/bottle