Oclatin Duo Dry Syrup (Amoxicillin Hydrate. Clavulanate Potassium (7:1))

Adult dose

For mild to moderate infections such as recurrent tonsillitis, upper respiratory tract infections, lower respiratory tract infections, urinary tract infections, and skin and soft tissue infections, administer amoxicillin/clavulanate potassium at a dosage of 25 mg/3.6 mg per kg of body weight daily, divided into 2 doses. For severe infections such as otitis media, sinusitis, lower respiratory tract infections like bronchopneumonia, and urinary tract infections, administer amoxicillin/clavulanate potassium at a dosage of 45 mg/6.4 mg per kg of body weight daily.

Child dose

The 7:1 syrup is not suitable for children under 2 months of age. It is also not suitable for pediatric patients with renal impairment.

This drug is a beta-lactam antibiotic and should not be administered to patients who have had hypersensitivity reactions to penicillin or cephalosporins. Patients with infectious mononucleosis or lymphocytic leukemia may have an increased risk of skin rash, so caution is warranted. Patients with a history of liver dysfunction or jaundice due to this medication or penicillin should avoid its use. This medication contains lactose, hence it should not be used in patients with genetic problems such as galactose intolerance, lactase deficiency, and glucose-galactose malabsorption. Patients with liver disease or moderate to severe renal dysfunction should use this medication cautiously, adjusting the dosing interval and dose as necessary. Individuals with allergic dispositions, elderly patients, or those with poor nutritional status may have an increased risk of bleeding due to vitamin K deficiency, necessitating caution. Patients experiencing vomiting or diarrhea may have insufficient drug absorption, so their condition should be assessed prior to administration. During the use of this medication, adverse reactions such as diarrhea, abdominal pain, rash, and urticaria may occur; if severe, it is crucial to stop taking the medication immediately and consult a physician. Symptoms of liver dysfunction may appear during treatment or up to 6 weeks after discontinuation, hence monitoring is necessary. Rarely, hypersensitivity reactions such as skin rashes or shock may occur, thus close observation of the patient's condition is essential after administering this medication. Prolonged use of this medication may lead to antibiotic resistance, so it is advisable to use it for the shortest necessary duration. If diarrhea worsens during or after antibiotic use, the possibility of pseudomembranous colitis should be considered, and immediate consultation with medical personnel is recommended. It is safer not to use this medication during the first three months of pregnancy, and caution is also required during breastfeeding, as diarrhea or allergic reactions may occur in the infant. Safety in premature infants or newborns under 2 months has not been established, so it is advisable to avoid administering it. This medication may interact with other drugs, so it is important to consult a healthcare professional when used alongside anticoagulants or certain antibiotics. In cases of overdose, symptoms such as gastrointestinal disturbance, renal dysfunction, and convulsions may occur, necessitating immediate medical attention for appropriate treatment. Shake well before use, and store in a tightly sealed container protected from air and moisture; it should be kept in a cool and dry place below 25 degrees Celsius and used within 7 days after preparation. Regular monitoring of liver and renal function, as well as blood tests, is crucial during the use of this medication, and any abnormal symptoms should be promptly reported to medical personnel.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe allergic reactions, high fever accompanied by severe rash, blisters, skin peeling, pain in oral/ocular mucosa, severe skin reactions, shortness of breath or difficulty in breathing, asthma attacks, respiratory problems accompanied by coughing and fever, yellowing of skin or eyes (jaundice), profound lethargy, liver dysfunction (jaundice), sudden

Mild side effects

• Diarrhea
• pseudomembranous colitis
• dyspepsia
• stomatitis
• gastritis
• glossitis
• black hairy tongue
• nausea
• vomiting
• loss of appetite

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture. It is advisable to keep it in a cool and dry place below 25 degrees Celsius.

Appearance

A white or pale yellow powder to be dissolved to prepare syrup for use

Package unit

50 milliliters/bottle [5.5g]