Oneverol Tablets (Carvedilol)

Adult dose

Do not increase the dose or stop taking this medicine without a doctor's instructions. 1. Essential hypertension 1) Adults (1) For the first 2 days, administer 12.5 mg of carvedilol orally once daily, then administer 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If an increase is needed, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. 2) Older adults In some older adults, 12.5 mg once daily may be sufficient to achieve an adequate response. If the response is inadequate after 2 weeks of treatment, the dose may be increased. 2. Chronic stable angina 1) For the first 2 days, administer 12.5 mg of this medicine per dose orally twice daily, then administer 25 mg per dose orally twice daily. 2) The usual dose is 25 mg per dose twice daily for 2 weeks. If an increase is needed (excluding older adults), the dose may be increased to 50 mg twice daily. 3. Congestive heart failure Before starting treatment with this medicine, the patient's existing standard therapy (conventional treatment for chronic heart failure with an ACE inhibitor, diuretic, and usually a digitalis preparation) should be stable. Fluid retention should also be minimized before starting treatment with this medicine. 1) The usual initial dose is 3.125 mg of this medicine per dose orally twice daily for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg twice daily for 2 weeks, then increase to 12.5 mg twice daily for 2 weeks, and then increase to 25 mg twice daily. 2) Increase the dose gradually after taking each dose level for at least 2 weeks, up to the dose tolerated by the patient. 3) The effective minimum dose is 6.25 mg per dose twice daily. The maximum dose is 25 mg per dose twice daily for patients weighing 85 kg or less, and 50 mg per dose twice daily for patients weighing more than 85 kg. 4) To control the rate of absorption, it is recommended to take the medicine with meals in the morning and evening. Taking it with meals slows the rate of absorption and may reduce the incidence of orthostatic hypotension.

This medication is often contraindicated in certain patients; for example, those who have allergies to this drug or its components, patients with severely impaired cardiac function, patients with asthma or severe respiratory disorders, and those with severe liver dysfunction should not receive it. Additionally, patients with diabetes, elderly individuals, and those with reduced kidney function should take special precautions when using this medication and should regularly monitor their blood pressure and cardiac condition. The drug can affect the central nervous system, leading to symptoms such as dizziness, headache, and fatigue, and may cause a slow heart rate or low blood pressure; therefore, if symptoms are severe, immediate consultation with a physician is necessary. Do not suddenly discontinue the medication while on it; doses should be gradually reduced under medical supervision, especially in patients with heart diseases, as abrupt withdrawal may worsen symptoms. This medication can interact with other drugs, so patients should inform their physician or pharmacist of any other medications they are taking. Caution is especially necessary when taken alongside antihypertensives, antidiabetics, cardiac medications, and sedatives. It is safer for pregnant or breastfeeding women not to use this medication, and its safety and efficacy in children and adolescents have not been adequately established. In case of overdose, there is a risk of severe hypotension, cardiac arrhythmias, and respiratory distress, so treatment should be sought immediately at a hospital, as this drug is not easily removed by dialysis. When storing this medication, keep it in a container that protects it from light exposure, and make sure to store it in a place out of reach of children. It is advisable to avoid transferring it to other containers.

• Dizziness
• headache
• fatigue
• weakness
• hallucinations
• confusion
• depression
• sleep disorders
• nightmares
• psychosis

This medication is sensitive to light, so it should be stored in a light-protective container. Additionally, it is best to keep the medication at room temperature between 1 to 30 degrees Celsius. This helps maintain the drug's efficacy for a longer period.

Appearance

White round tablets

Package unit

90 tablets (10 tablets/ PTP X 9)