Unityaxone Injection 1 Gram (Ceftriaxone Sodium Hydrate)

Adult administration

For adults and children over 12 years, administer 1-2g (potency) of ceftriaxone once daily by intravenous or intramuscular injection. For infections caused by severe pathogens or moderately sensitive strains, the dose may be increased to 4g (potency) once daily. For meningitis, the initial dose is 100mg (potency) per kg body weight, not exceeding a total of 4g (potency) per day. For gonorrhea treatment, 250 mg (potency) as a single intramuscular injection is recommended.

Child administration

For newborns (up to 14 days old), 20-50mg (potency) per kg body weight is administered once daily, not exceeding 50mg (potency) per kg. Infants and children (15 days to 12 years) should receive dosage based on body weight.

This medication should not be mixed or administered simultaneously with solutions or drugs containing calcium. In particular, it must never be administered to newborns, as it can form precipitates when combined with calcium, resulting in life-threatening side effects. Individuals who are allergic to this medication or have had hypersensitivity reactions to cephalosporin or penicillin antibiotics should not use it. Caution should also be exercised for individuals allergic to the local anesthetic lidocaine, and it is not administered to premature infants or newborns with bilirubin-related disorders. Patients with a history of hypersensitivity or allergies, those with poor kidney function, elderly individuals, and patients in poor general condition should use this medication with caution, and dosage adjustment and regular monitoring may be necessary. This medication may have various side effects, including common occurrences of changes in blood cell counts, diarrhea, rash, and liver function abnormalities. Rarely, serious allergic reactions, kidney damage, hepatitis, or skin disorders may occur, so if any abnormal symptoms appear, consult a physician immediately. This medication should only be used for the required duration to prevent the emergence of resistant bacteria, and its administration should be preceded by verification of allergies and followed by close monitoring of the patient's condition. Moreover, regular blood tests and monitoring of liver and kidney functions are advised. Safety during pregnancy has not been established, so pregnant women should consult a physician before administration, and nursing mothers should also be cautious. Use in newborns or premature infants should be particularly careful, and it should not be used in newborns with elevated bilirubin levels. During the administration of this drug, caution is advised when driving or operating machinery due to possible side effects like dizziness. Caution is needed when using this drug with others due to the risk of kidney function deterioration or drug interactions, especially with diuretics, aminoglycoside antibiotics, vitamin K antagonists, and others. This medication should be used as soon as possible after preparation, and appropriate temperature should be maintained during storage. Also, care should be taken not to administer it with solutions containing calcium.

Serious side effects

Hives, severe swelling (edema), cold sweat, chest tightness, difficulty breathing, high fever with severe rash, blisters, skin peeling, pain in mucous membranes of mouth/eyes, anaphylaxis and anaphylactoid reactions, liver abnormalities (jaundice), sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, significant reduction in urine output, severe swelling accompanied by high blood pressure, kidney abnormalities (acute renal failure), encephalopathy.

Mild side effects

• Eosinophilia
• leukopenia
• thrombocytopenia
• diarrhea
• rash
• increased liver enzymes
• genital fungal infection
• pseudomembranous colitis
• agranulocytosis
• anemia

This medication should be stored in a sealed container to prevent exposure to air or moisture. Additionally, it is best stored at room temperature between 1 degree and 30 degrees. Proper storage helps maintain the medication's effectiveness and prevents degradation.

Appearance

[For Domestic Sale] A colorless transparent vial containing a white to light yellow powder. [For Export 1] A colorless transparent vial containing a white to light yellow powder, and a colorless transparent ampoule containing a colorless transparent solvent.

Package unit

[For Domestic Sale] - 10 vials/box [(1 gram/vial) x10], [For Export 2] - 10 vials/box [(1 gram/vial)*10], [For Export 1] - 1 package/box [(1 gram/vial x1)+attached solvent 10 milliliters/ampoule x1)x1]