Carvedilol 25 mg Tablet

Adult dose

Do not increase the dose or stop taking this medicine without your doctor's instructions. 1. Essential hypertension 1) Adults (1) For the first 2 days, administer 12.5 mg of carvedilol orally once daily, then administer 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is needed, increase to 25 mg per dose twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. 2) Elderly patients Some elderly patients may achieve sufficient effect with a dose of 12.5 mg once daily. However, if the effect is insufficient after 2 weeks of treatment, the dose may be increased. 2. Chronic stable angina 1) For the first 2 days, administer 12.5 mg of this medicine per dose twice daily orally, then administer 25 mg per dose twice daily orally. 2) The usual dose is 25 mg per dose twice daily for 2 weeks. If a dose increase is needed (excluding elderly patients), the dose may be increased up to 50 mg per dose twice daily. 3. Congestive heart failure Before starting treatment with this medicine, the patient's existing standard therapy (conventional treatment for chronic heart failure with an ACE inhibitor, a diuretic, and usually a digitalis preparation) must be stable. Fluid retention should also be minimized before starting treatment with this medicine. 1) The usual initial dose is 3.125 mg of this medicine per dose, twice daily orally for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg per dose twice daily for 2 weeks, then increase to 12.5 mg per dose twice daily for 2 weeks, and then increase to 25 mg per dose twice daily. 2) After taking each dose for at least 2 weeks, gradually increase the dose to the level tolerated by the patient. 3) The minimum effective dose is 6.25 mg per dose twice daily. The maximum dose is 25 mg per dose twice daily for patients weighing 85 kg or less, and 50 mg per dose twice daily for patients weighing more than 85 kg. 4) To control the rate of absorption, it is recommended to take this medicine with meals in the morning and evening. Taking it with meals slows the rate of absorption and may reduce the incidence of orthostatic hypotension.

This medication should not be administered to certain patients. For example, patients allergic to this drug or its ingredients, those in a state of cardiogenic shock, and those with severe heart conduction disorders may be at risk if they use this medication. Additionally, patients with bronchial asthma or chronic obstructive pulmonary disease, pregnant or breastfeeding women, and patients with severe liver dysfunction should also avoid taking this medicine. Care should be taken when administering this medication to patients with diabetes, elderly patients, patients with impaired kidney function, and those with low blood pressure. Especially, patients with weakened heart function or low blood pressure should consult a doctor before taking it and be carefully monitored. This medication can have central nervous system side effects such as dizziness, fatigue, and headache, as well as cardiovascular adverse reactions including decreased heart rate and blood pressure, and worsening heart failure. Therefore, heart rate and blood pressure should be monitored regularly during treatment, and if any unusual symptoms occur, the doctor should be consulted immediately. Furthermore, this medication may also affect liver and kidney function, so regular liver and kidney function tests are important during long-term use. This medication interacts with many other drugs, potentially altering its effectiveness or increasing the risk of side effects when combined. Therefore, it is essential to inform the doctor or pharmacist of any other medications being taken and to monitor carefully during concomitant drug therapy. Women who are pregnant or breastfeeding should not take this medication, and those planning pregnancy should consult a doctor before use. Safety and efficacy have not been sufficiently established for children or adolescents under 18 years of age, and it is not recommended for them. In case of overdose, severe hypotension, decreased heart rate, and reduced heart function may occur, requiring immediate medical assistance, and emergency treatment may be necessary. This medication is sensitive to light, so it should be stored in a light-blocking container and kept out of reach of children. Patients should not suddenly discontinue this medication; dosage should be gradually reduced according to the doctor's instructions, especially since patients with heart disease are at risk for worsening symptoms. Caution is advised while driving or operating hazardous machinery, as symptoms such as dizziness or drowsiness may occur. It is crucial to have regular check-ups and symptom monitoring during treatment with this medication to ensure safe therapy.

• Dizziness
• headache
• fatigue
• weakness
• hallucinations
• confusion
• depression
• sleep disorders
• nightmares
• psychosis

This medication is sensitive to light and should be stored in an airtight container that blocks light. It should also be kept at room temperature, maintaining a temperature between 1°C and 30°C.

Appearance

White round tablet

Package unit

100 tablets (10 tablets/PTP x 10)