Medication info
Nexium Tablet 40 Milligrams (Esomeprazole Magnesium)

Nexium Tablet 40 Milligrams (Esomeprazole Magnesium)

Prescription medicationTablet
Ingredient · strength
Esomeprazole Magnesium Trihydrate›44.5mg
Manufacturer / importer
한국아스트라제네카(주)
Appearance
Pink rectangular film-coated tablet
Packaging
14 tablets (7 tablets/PTP x 2)
Approval status
Active

MFDS item code 200009026 · Approved 2000.10.19 · Insurance code 650700080

Summary

Main use
Treatment and prevention of recurrence of gastroesophageal reflux disease (including erosive reflux esophagitis), treatment and prevention of recurrence of benign peptic ulcers associated with Helicobacter pylori, relief of gastrointestinal symptoms related to nonsteroidal anti-inflammatory drugs and prevention of ulcer.
Who uses it
Adults · Children
Adult dosage
This medication should be swallowed with liquid such as water and should not be chewed or crushed. Patients who find it difficult to swallow the tablet can dissolve it in half a cup of non-carbonated water. Other beverages should not be used as they may dissolve the enteric coating. Stir until dissolved and drink immediately or within 30 minutes without chewing, rinsing the cup with half a cup of non-carbonated water afterward. Do not chew or crush the floating particles during ingestion.
Children's dosage
Adolescents aged 12 years and older - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks; if symptoms persist or are not resolved, an additional 4 weeks of treatment. - Symptomatic treatment for gastroesophageal reflux disease without esophagitis.

Ingredients

Importer
한국아스트라제네카(주)

Efficacy & effects

Treatment and prevention of recurrence of gastroesophageal reflux disease (including erosive reflux esophagitis), treatment and prevention of recurrence of benign peptic ulcers associated with Helicobacter pylori, relief of gastrointestinal symptoms related to nonsteroidal anti-inflammatory drugs and prevention of ulcer.

  • Gastroesophageal reflux disease
  • erosive reflux esophagitis
  • esophagitis
  • duodenal ulcers
  • peptic ulcers
  • upper gastrointestinal pain
  • upper gastrointestinal discomfort
  • upper gastrointestinal burning sensation
  • gastric ulcers
  • duodenal ulcers
  • Zollinger-Ellison syndrome
  • rebleeding of gastric ulcers
View approved original text

This medication is used to treat gastroesophageal reflux disease and erosive reflux esophagitis, and for long-term maintenance therapy to prevent relapse in patients with esophagitis. It is also included in combination antibiotic therapy for the eradication of Helicobacter pylori, effective for the treatment and prevention of relapse of duodenal ulcers and peptic ulcers. Additionally, it helps in the treatment and prevention of upper gastrointestinal symptoms or ulcers due to the use of nonsteroidal anti-inflammatory drugs. It is also used for the treatment of Zollinger-Ellison syndrome and for maintenance therapy to prevent rebleeding after intravenous administration. Overall, it is used for the treatment and prevention of various gastrointestinal-related diseases.

Dosage and Administration

Adult dosage

This medication should be swallowed with liquid such as water and should not be chewed or crushed. Patients who find it difficult to swallow the tablet can dissolve it in half a cup of non-carbonated water. Other beverages should not be used as they may dissolve the enteric coating. Stir until dissolved and drink immediately or within 30 minutes without chewing, rinsing the cup with half a cup of non-carbonated water afterward. Do not chew or crush the floating particles during ingestion.

Children's dosage

Adolescents aged 12 years and older - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks; if symptoms persist or are not resolved, an additional 4 weeks of treatment. - Symptomatic treatment for gastroesophageal reflux disease without esophagitis.

Precautions

This medication should not be administered to certain patients. Patients who have had allergies or hypersensitivity to this drug, its components, or similar class of medications should not use it. Additionally, caution is required when taken with certain antibiotics or antiviral drugs due to the risk of side effects or interactions. Women who are breastfeeding or patients with a history of myocardial infarction should also avoid using this medication. This medication may cause various side effects. Gastrointestinal symptoms such as headache, abdominal pain, diarrhea, nausea, and vomiting are commonly reported, while rarely, blood-related abnormalities, hypersensitivity reactions, or hypomagnesemia may occur. Mental changes, skin rashes, hair loss, muscle pain may also appear, so consult a medical professional immediately if abnormal symptoms occur. Regular check-ups are required for long-term use. Especially if taken for over a year, the risk of hypomagnesemia or fractures may increase, so constant monitoring is necessary. This medication suppresses gastric acid secretion, which may promote bacterial growth in the gastrointestinal tract, thus slightly increasing the risk of gastrointestinal infections. If diarrhea persists or worsens, it is essential to consult a doctor. Moreover, this medication can interact with several other drugs, so inform healthcare professionals if you are taking other medications. Care should be taken when used with drugs affecting blood coagulation, antiviral drugs, or specific antibiotics. Safety data regarding use during pregnancy is limited, so if pregnant or planning to become pregnant, consult a healthcare professional before use, and its use is not recommended during breastfeeding. In case of overdose, since there is no specific antidote, appropriate treatment should be received according to the symptoms, and it should be stored out of reach of children. Transferring to another container may pose a risk of accidents and quality degradation.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, anaphylaxis reaction/shock, severe rash with high fever, blisters, skin peeling, pain in mouth/eyes mucosa, erythema multiforme, systemic lupus erythematosus, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome), acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), shortness of breath.

Mild side effects

  • Headache
  • dizziness
  • paresthesia
  • drowsiness
  • taste disturbance
  • blurred vision
  • bronchospasm
  • abdominal pain
  • constipation
  • diarrhea
Show 30 more
  • abdominal bloating
  • nausea
  • vomiting
  • dry mouth
  • stomatitis
  • elevated liver enzymes
  • dermatitis
  • itching
  • rash
  • alopecia
  • photosensitivity
  • fractures
  • arthralgia
  • myalgia
  • muscle weakness
  • asthenia
  • increased sweating
  • fever
  • elevated blood pressure
  • fatigue
  • pain
  • stiffness
  • insomnia
  • anxiety
  • confusion
  • depression
  • aggression
  • hallucinations
  • loss of appetite
  • apathy

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it should be stored in a sealed container. It is advisable to store it at room temperature, not in excessively hot or cold places.

Appearance and packaging

Appearance

Pink rectangular film-coated tablet

Package unit

14 tablets (7 tablets/PTP x 2)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

No questions yet.

For anything that needs medical judgment, consult a doctor or pharmacist.

Related searches

Search tags

Suggested searches

This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.