Hanlim Romefloxacin Hydrochloride Tablet 200 mg

Adult dose

1. Administer 100 ～ 200 mg of lomefloxacin orally 2 ～ 3 times daily. 2. However, for acute exacerbation of chronic obstructive pulmonary disease, including chronic bronchitis, the usual adult dose is 400 mg of this medicine once daily, taken with or without food. The duration of treatment varies depending on the severity of the infection, but is usually up to 14 days; treatment should continue for at least 2 days after the symptoms of infection have resolved. 3. Patients with renal impairment 1) In patients with a creatinine clearance of less than 30 mL per minute, administer 400 mg of this medicine as a single initial dose, followed by 200 mg once daily starting the next day. 2) In patients on hemodialysis, administer 400 mg of this medicine as a single initial dose, followed by 200 mg once daily starting the next day. 3) No dose adjustment is necessary in patients with hepatic impairment; adjust the dose according to renal function.

This drug may cause serious side effects such as tendonitis or tendon rupture, peripheral neuropathy, and central nervous system abnormalities. If these symptoms appear, the use of this drug should be stopped immediately. This drug is not administered to patients with myasthenia gravis as it may worsen symptoms. Furthermore, it is only used for acute bacterial sinusitis, acute exacerbation of chronic bronchitis, uncomplicated urinary tract infections, and acute otitis media when no other treatment options are available. Elderly patients, patients with reduced kidney function, transplant recipients, or those taking corticosteroids may have an increased risk of tendon rupture, so concomitant use should be avoided. If symptoms of tendonitis or tendon rupture occur, rest should be taken and strenuous exercise should be avoided. This drug should not be used by individuals with hypersensitivity to it, growing adolescents under the age of 18, pregnant women, lactating women, or patients with a history of tendonitis or rupture from previous use of this drug. Caution should be exercised when administering to patients with a history of epilepsy or seizures, severe renal impairment, the elderly, or those with aortic aneurysm or heart valve disease. This drug can cause various side effects such as anaphylactic shock, skin rash, photosensitivity, gastrointestinal disturbances, kidney and liver function abnormalities, central nervous system abnormalities, and respiratory problems; therefore, any abnormal symptoms should be reported to a healthcare professional immediately. Additionally, this medication may react sensitively to sunlight or ultraviolet rays, so exposure to strong sunlight should be avoided, and care should be taken when driving or operating machinery due to the risk of dizziness. Diabetic patients whose blood sugar levels need to be controlled should be cautious of blood sugar fluctuations and must disclose any concurrent medications as interactions may occur. Pregnant or breastfeeding women should avoid using this drug, and it is not recommended for children or adolescents as safety has not been proven. Elderly patients may experience an increased drug concentration due to reduced renal function, necessitating dose adjustment and caution. In cases of overdose, emergency measures such as inducing vomiting or gastric lavage should be taken, while hemodialysis is not effective for drug removal. Lastly, prolonged use of this drug may increase the risk of skin cancer due to UV exposure, so caution is advised.

• Tendonitis
• tendon rupture
• peripheral neuropathy
• central nervous system effects
• exacerbation of myasthenia gravis
• anaphylactic shock
• anaphylactoid reactions
• rash
• urticaria
• erythema

This drug is sensitive to light and should be stored in a sealed container that blocks light. The storage temperature should be kept between 1 to 30 degrees Celsius, and extreme hot or cold conditions should be avoided.

Appearance

White oval film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle