Medication info
Carvedilol Tablets 25 mg (Carvedilol)

Carvedilol Tablets 25 mg (Carvedilol)

Prescription medicationTabletOral
Ingredient · strength
Carvedilol›25mg / 1 tablet
Manufacturer / importer
Hanmi Pharmaceutical Co., Ltd.
Appearance
White round tablet
Packaging
100 tablets (10 tablets/PTP x 10)/carton
Approval status
Active

MFDS item code 200003080 · Notified 2000.05.30 · Insurance code 643502390

Summary

Main use
Adjunctive treatment of congestive heart failure; treatment of essential hypertension and chronic stable angina
Who takes it
Adults
Adult dose
Do not increase the dose or stop taking this medicine without your doctor's instructions. 1. Essential hypertension 1) Adults (1) Administer 12.5 mg of carvedilol orally once daily for the first 2 days, then administer 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is needed, increase to 25 mg twice daily. The maximum dose is 25 mg per dose and 50 mg per day. 2) Elderly patients For some elderly patients, 12.5 mg once daily may be sufficient. However, if the effect is insufficient after 2 weeks of treatment, the dose may be increased. 2. Chronic stable angina 1) Administer 12.5 mg of this medicine twice daily for the first 2 days, then administer 25 mg twice daily. 2) The usual dose is 25 mg twice daily for 2 weeks. If a dose increase is needed (excluding elderly patients), the dose may be increased up to 50 mg twice daily. 3. Congestive heart failure 1) For initial treatment, the usual dose is 3.125 mg of this medicine twice daily for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg twice daily for 2 weeks, then to 12.5 mg twice daily for 2 weeks, and then to 25 mg twice daily. 2) After taking each dose for at least 2 weeks, gradually increase the dose to the highest dose the patient can tolerate. 3) The minimum effective dose is 6.25 mg twice daily. The maximum dose is 25 mg twice daily for patients weighing 85 kg or less and 50 mg twice daily for patients weighing more than 85 kg. 4) To regulate the rate of absorption, it is recommended to take the medicine with meals in the morning and evening.

Ingredients

Manufacturer
Hanmi Pharmaceutical Co., Ltd.

Efficacy & effects

Adjunctive treatment of congestive heart failure; treatment of essential hypertension and chronic stable angina

  • Essential hypertension
  • chronic stable angina
  • congestive heart failure
View approved original text

This medication is used to treat essential hypertension, chronic stable angina, and congestive heart failure. It is particularly utilized as an adjunct therapy to improve cardiovascular health in combination with diuretics, digitalis glycosides, ACE inhibitors, and other vasodilators.

How to take

Adult dose

Do not increase the dose or stop taking this medicine without your doctor's instructions. 1. Essential hypertension 1) Adults (1) Administer 12.5 mg of carvedilol orally once daily for the first 2 days, then administer 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is needed, increase to 25 mg twice daily. The maximum dose is 25 mg per dose and 50 mg per day. 2) Elderly patients For some elderly patients, 12.5 mg once daily may be sufficient. However, if the effect is insufficient after 2 weeks of treatment, the dose may be increased. 2. Chronic stable angina 1) Administer 12.5 mg of this medicine twice daily for the first 2 days, then administer 25 mg twice daily. 2) The usual dose is 25 mg twice daily for 2 weeks. If a dose increase is needed (excluding elderly patients), the dose may be increased up to 50 mg twice daily. 3. Congestive heart failure 1) For initial treatment, the usual dose is 3.125 mg of this medicine twice daily for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg twice daily for 2 weeks, then to 12.5 mg twice daily for 2 weeks, and then to 25 mg twice daily. 2) After taking each dose for at least 2 weeks, gradually increase the dose to the highest dose the patient can tolerate. 3) The minimum effective dose is 6.25 mg twice daily. The maximum dose is 25 mg twice daily for patients weighing 85 kg or less and 50 mg twice daily for patients weighing more than 85 kg. 4) To regulate the rate of absorption, it is recommended to take the medicine with meals in the morning and evening.

Precautions

This medication should not be used in certain patients. For example, patients who have allergies to this medication or its components, patients with cardiogenic shock, those with heart conduction issues, patients with cor pulmonale, patients with diabetic ketoacidosis, those with severely weakened heart function, patients with asthma or chronic obstructive pulmonary disease, patients with secondary hypertension, patients with Prinzmetal angina, patients with acute pulmonary embolism, patients with pheochromocytoma, those taking certain medications, patients with severe hypotension, patients with severe liver impairment, pregnant or breastfeeding women, patients with peripheral circulation disorders, patients with laryngeal edema, patients with complications from heart attacks, patients with severe fluid retention, patients with allergic rhinitis, and lactose intolerant patients should not receive this medication. In addition, patients with diabetes or a history of hypersensitivity reactions, patients with a history of psoriasis triggered by beta-blockers, patients with low blood pressure and other cardiovascular diseases, patients with unstable angina, patients with chronic congestive heart failure, patients with severe renal impairment, patients with atrioventricular block, elderly patients, patients prone to sudden drops in blood pressure, patients with acute heart diseases, and those taking certain medications concomitantly should be administered with caution and under strict medical supervision. When taking this medication, various side effects may occur, such as dizziness, headache, fatigue, decreased heart rate, reduced blood pressure, worsening heart failure, renal function decline, respiratory issues, gastrointestinal symptoms, skin rashes, liver function abnormalities, hematological issues, endocrine problems, etc. If abnormal symptoms appear, consult a doctor immediately. With long-term use, regular monitoring of heart function as well as blood pressure, heart rate, and liver and kidney function tests is essential. Do not abruptly discontinue the medication; gradually reduce the dosage according to the doctor's instructions. Additionally, caution is needed when driving or operating hazardous machinery as dizziness or drowsiness may occur. This medication may interact with other drugs, so it is essential to inform your doctor of any other medications you are taking, especially when taking blood pressure medications, antidepressants, sedatives, calcium channel blockers, hypoglycemic agents, anesthetics, alcohol, etc. Pregnant or breastfeeding women should not take this medication, and safety for children and adolescents under 18 years has not been established. Elderly patients should start with a lower dosage due to the potential for increased drug concentrations from liver function decline and should be administered cautiously. In cases of overdose, symptoms may include lower blood pressure, reduced heart rate, impaired heart function, shock, respiratory distress, and altered consciousness. In such cases, seek appropriate medical treatment immediately. This medication is sensitive to light, hence should be stored in a light-proof container, kept out of reach of children, and not transferred to another container for safety.

Side effects

  • Dizziness
  • headache
  • fatigue
  • weakness
  • hallucinations
  • confusion
  • depression
  • sleep disorders
  • nightmares
  • psychosis
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  • severe bradycardia
  • shock
  • complete atrioventricular block
  • heart failure
  • cardiac arrest
  • significant decrease in blood pressure
  • loss of consciousness
  • decreased pulse rate
  • cold extremities
  • edema
  • cardiac arrest
  • worsening of kidney function
  • kidney failure
  • increased respiratory tract resistance
  • nausea
  • diarrhea
  • abdominal pain
  • vomiting
  • constipation
  • hives
  • itching
  • lichenoid reaction
  • sweating
  • allergic rash
  • serum aminotransferase changes
  • thrombocytopenia
  • leukopenia
  • hypoglycemia
  • masking of hyperthyroidism
  • hyperglycemia
  • weight gain
  • increased blood cholesterol
  • bradycardia
  • hypotension
  • shortness of breath
  • hypertension in angina
  • liver dysfunction
  • jaundice
  • limb pain
  • decreased tears
  • sensory disturbances
  • visual disturbances
  • eye irritation
  • dry mouth
  • urinary disorders
  • sexual dysfunction
  • allergic reactions
  • toxic epidermal necrolysis
  • Stevens-Johnson syndrome
  • marked drop in blood pressure
  • slowed heartbeat
  • myocardial depression
  • cardiac arrest
  • dyspnea
  • bronchospasm
  • vomiting
  • consciousness disorder
  • generalized seizure

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light and should be stored in an airtight container that blocks light. Additionally, it is important to maintain storage temperatures between 1 degree Celsius and 30 degrees Celsius to preserve the medication's effectiveness.

Appearance and packaging

Appearance

White round tablet

Package unit

100 tablets (10 tablets/PTP x 10)/carton

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.