Medication info

Seretide 250 Diskus

Prescription medicationApproval withdrawn
Ingredient · strength
Salmeterol Xinafoate Micronized›72.5μgFluticasone Propionate Micronized›250μg
Manufacturer / importer
(주)글락소스미스클라인
Appearance
An inhaler with a purple round plastic device containing a filled pouch of white powder.
Packaging
60 doses/container, 28 doses/container
Approval status
Approval withdrawn

MFDS item code 199907431 · Approved 1999.07.24

This product's status changed to Approval withdrawn on 2024.10.30. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of asthma (bronchodilation, inflammation) and improvement of airflow obstruction in chronic obstructive pulmonary disease.
Who uses it
Adults · Children
Adult dosage
For adults and children over 12 years with asthma: Inhale Salmeterol 50 μg + Fluticasone propionate 100 μg twice daily, or Salmeterol 50 μg + Fluticasone propionate 250 μg twice daily, or Salmeterol 50 μg + Fluticasone propionate 500 μg twice daily. For adults with chronic obstructive pulmonary disease: Salmeterol 50 μg + Fluticasone propionate 250 μg twice daily. In elderly or renal failure patients, dosage adjustments are necessary, and there is a lack of useful data regarding the use of this medication in hepatic failure patients.
Children's dosage
For children aged 4 to 11 years with asthma: Inhale Salmeterol 50 μg + Fluticasone propionate 100 μg twice daily. There is a lack of useful data regarding the use of this medication in children under 4 years of age.

Ingredients

Importer
(주)글락소스미스클라인

Efficacy & effects

Treatment of asthma (bronchodilation, inflammation) and improvement of airflow obstruction in chronic obstructive pulmonary disease.

  • Asthma
  • chronic bronchitis
  • chronic obstructive pulmonary disease
  • airway obstruction
View approved original text

This medication is used in patients with asthma who require treatment with both a bronchodilator and an inhaled corticosteroid. It is also used as a maintenance therapy to treat airflow obstruction in patients with chronic obstructive pulmonary disease associated with chronic bronchitis. Specifically, it helps improve breathing by widening the airways and alleviating chronic inflammation, thus improving symptoms. This treatment can reduce breathlessness and enhance quality of life. Therefore, this medication is used effectively to treat respiratory symptoms in patients with asthma and chronic obstructive pulmonary disease.

Dosage and Administration

Adult dosage

For adults and children over 12 years with asthma: Inhale Salmeterol 50 μg + Fluticasone propionate 100 μg twice daily, or Salmeterol 50 μg + Fluticasone propionate 250 μg twice daily, or Salmeterol 50 μg + Fluticasone propionate 500 μg twice daily. For adults with chronic obstructive pulmonary disease: Salmeterol 50 μg + Fluticasone propionate 250 μg twice daily. In elderly or renal failure patients, dosage adjustments are necessary, and there is a lack of useful data regarding the use of this medication in hepatic failure patients.

Children's dosage

For children aged 4 to 11 years with asthma: Inhale Salmeterol 50 μg + Fluticasone propionate 100 μg twice daily. There is a lack of useful data regarding the use of this medication in children under 4 years of age.

Precautions

This medication works to dilate the bronchi to ease breathing, but it takes about 10 to 20 minutes for the effects to manifest, so it should not be used in cases of acute asthma attacks or severe asthma exacerbations that pose a threat to life. This medication is not for the treatment of acute asthma, and a fast-acting separate inhaler should be used for quick relief of acute symptoms. It should not be used in individuals with allergies to any component of the product or specific conditions such as heart arrhythmias, untreated respiratory infections, or severe bronchiectasis. Patients with a history of heart disease, diabetes, hyperthyroidism, seizure disorders, pulmonary tuberculosis, or hypokalemia should use this medication cautiously, and may need regular check-ups upon the doctor's advice. Rarely, after using this medication, side effects such as dyspnea, bronchospasm, oral candidiasis, palpitations, headaches, myalgia, skin rashes may occur, and if any unusual symptoms arise, immediate consultation with a healthcare provider is required. After inhalation, it is important to rinse the mouth thoroughly to prevent oral candidiasis, and it is crucial to learn and follow the proper administration method. This medication may interact with other beta-2 agonists or specific drugs, so if there are other medications being taken, it is essential to inform the physician or pharmacist. In cases of pregnancy or breastfeeding, the use of this medication should be discussed thoroughly regarding its effects on the fetus or newborn, and particular caution is needed for pediatric and elderly patients. Overuse of this medication can lead to serious side effects such as heart problems, glucose changes, and hypokalemia, so it is vital to adhere strictly to the prescribed dosage and frequency. Patients with asthma or chronic obstructive pulmonary disease should always carry a quick-relief inhaler while using this medication and should seek immediate evaluation by healthcare providers in case of symptom exacerbation. This medication should only be used for oral inhalation and cannot be effective if taken orally or through any other method. When storing, it should be kept in a cool place out of reach of children, and it is advisable to check the number of doses remaining before use.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rash with high fever, blisters, skin peeling, pain in mouth/eye mucosa, severe skin adverse reactions, difficulty or shortness of breath, asthma attack, abnormal breathing accompanied by cough and fever, jaundice (yellowing of skin or eyes), profound lethargy, liver abnormalities (jaundice), sudden and severe reactions.

Mild side effects

  • Nausea
  • vomiting
  • diarrhea
  • abdominal pain
  • headache
  • tremors
  • awareness of palpitations
  • palpitations
  • tachycardia
  • atrial fibrillation
Show 24 more
  • nonspecific chest pain
  • blood pressure changes
  • bronchitis
  • rhinitis
  • laryngitis
  • oral and throat irritation
  • abdominal pain
  • muscle contractions
  • myalgia/myositis
  • muscle soreness
  • joint pain
  • muscle cramps
  • menstrual irregularities
  • redness
  • rash
  • angioedema
  • irritation
  • toothache
  • hyperglycemia
  • hoarseness/voice disorders
  • oral and throat candidiasis
  • skin hypersensitivity reactions
  • anxiety
  • sleep disturbances.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light, so it should be stored in a container that does not allow light to enter. Furthermore, to maintain its efficacy, it is important to store it at room temperature, specifically between 1 and 30 degrees Celsius.

Appearance and packaging

Appearance

An inhaler with a purple round plastic device containing a filled pouch of white powder.

Package unit

60 doses/container, 28 doses/container

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

No questions yet.

For anything that needs medical judgment, consult a doctor or pharmacist.

Related searches

Search tags

Suggested searches

This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.