Medication info
Levofloxacin Tablet (Levofloxacin Hydrate)

Levofloxacin Tablet (Levofloxacin Hydrate)

Prescription medicationTablet
Ingredient · strength
Levofloxacin Hydrate›100mg / 1 tablet
Manufacturer / importer
(주)에이프로젠바이오로직스
Appearance
White, round, film-coated tablet
Packaging
30, 300 tablets/bottle
Approval status
Active

MFDS item code 199900886 · Notified 1999.04.15 · Insurance code 645200570

Summary

Main use
Treatment of complicated skin and soft tissue infections and secondary infections in chronic respiratory diseases
Who uses it
Adults
Adult dosage
Tablet 100 mg: For ordinary adults, 100 mg is taken orally 2-3 times a day as levofloxacin. In severe cases or when the effect is insufficient, 200 mg is taken orally 3 times a day. Tablets 250, 500 mg: For ordinary adults, 250-750 mg is taken orally once daily as levofloxacin. Dosage adjustment is needed based on renal function. Injection: administered via drip intravenous infusion 1-2 times a day

Ingredients

Manufacturer
(주)에이프로젠바이오로직스

Efficacy & effects

Treatment of complicated skin and soft tissue infections and secondary infections in chronic respiratory diseases

  • Complicated skin and soft tissue infections
  • chronic bronchitis
  • diffuse bronchitis
  • secondary infections in chronic respiratory diseases
  • community-acquired pneumonia
  • bronchiectasis (during infection)
  • acute pyelonephritis
  • cystitis
  • prostatitis
  • gonococcal urethritis
  • non-gonococcal urethritis
  • epididymitis
View approved original text

This medication is effective against various bacteria and is used for the treatment of complicated skin and soft tissue infections, as well as secondary infections in respiratory diseases like chronic bronchitis or pneumonia. It also helps treat urinary tract infections such as acute pyelonephritis, cystitis, and prostatitis, as well as gonococcal and non-gonococcal urethritis. It is effective against bacterial dysentery, gastroenteritis, pelvic inflammatory disease, intrauterine infections, and ophthalmic conditions like blepharitis or styes. It is used to alleviate symptoms of infections in various areas, including otitis media, sinusitis, periodontitis, osteomyelitis, cholecystitis, and cholangitis. However, this medication is a fluoroquinolone and has a risk of serious side effects, so it should be used cautiously when there are no alternative treatments for some infections. Overall, it is used to improve various infectious diseases.

Dosage and Administration

Adult dosage

Tablet 100 mg: For ordinary adults, 100 mg is taken orally 2-3 times a day as levofloxacin. In severe cases or when the effect is insufficient, 200 mg is taken orally 3 times a day. Tablets 250, 500 mg: For ordinary adults, 250-750 mg is taken orally once daily as levofloxacin. Dosage adjustment is needed based on renal function. Injection: administered via drip intravenous infusion 1-2 times a day

Precautions

This medication is a fluoroquinolone antibiotic and may cause tendon-related problems such as tendonitis or tendon rupture. If pain or inflammation occurs in the tendons while taking this medication, use should be discontinued immediately and consultation with a healthcare professional is advised. Peripheral neuropathy and central nervous system symptoms may also occur, so caution is advised if sensory abnormalities or neurological symptoms develop. Patients with myasthenia gravis should avoid using this medication as symptoms may worsen. This medication is used only for specific infections and should be administered only when no alternative treatment is available. Caution is required in elderly patients, those with impaired kidney function, and when used concurrently with corticosteroids as the risk of tendon rupture may increase. Pregnant or breastfeeding women, as well as children and adolescents in growth, should not use this medication. Serious allergic reactions, psychiatric symptoms, liver dysfunction, blood abnormalities, gastrointestinal disturbances, skin rashes, and various other side effects may occur during use; any abnormal symptoms should be reported to a healthcare professional immediately. Additionally, this medication may cause photosensitivity reactions, so exposure to strong sunlight or artificial ultraviolet light should be avoided. Dizziness or drowsiness may occur when driving or operating machinery; caution is advised. There are many potential drug interactions, especially with anticoagulants, hypoglycemics, antacids, so consultation with a healthcare professional is required when taking them together. In case of overdose, central nervous system symptoms and cardiac irregularities may occur, so it is crucial to adhere to the prescribed dosage and administration.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, paleness, severe rash with fever, blisters, skin peeling, oral/ocular mucosal pain, shortness of breath or difficulty breathing, asthma attacks, cough with fever and respiratory abnormalities, yellowing of the skin or eyes (jaundice), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, altered consciousness, vision problems, paralysis, urinary problems

Mild side effects

  • Insomnia
  • dizziness
  • headache
  • tremors
  • anxiety
  • depression
  • psychotic reactions
  • restlessness
  • confusion
  • seizures
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  • visual and auditory disturbances
  • taste and smell disturbances
  • hallucinations
  • mania
  • paresthesia
  • sensory impairment
  • weakness
  • palpitations
  • QT interval prolongation
  • arrhythmia
  • increased BUN and serum creatinine
  • leukopenia
  • erythrocytopenia
  • hemoglobin decrease
  • hematocrit decrease
  • eosinophilia
  • anemia
  • thrombocytopenia
  • nausea

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent air from entering, and it is best kept at room temperature between 1°C and 30°C. Storing it this way helps maintain the effectiveness of the medication for a longer period.

Appearance and packaging

Appearance

White, round, film-coated tablet

Package unit

30, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.