Rectasin Tablet (Levofloxacin Hydrate)

Adult dosage

Typically, adults take 100 mg of levofloxacin orally, 2-3 times a day. For patients with severe conditions or inadequate response, the dose is increased to 200 mg per dose, 3 times daily. Adjust as appropriate based on age and symptoms.

This drug is a fluoroquinolone antibiotic and may cause serious side effects such as tendonitis or tendon rupture, peripheral neuropathy, central nervous system disturbances, and exacerbation of myasthenia gravis. If any of these symptoms occur, the medication should be stopped immediately, and it is not to be administered to patients with myasthenia gravis. Additionally, it is used restrictively for certain bacterial infections like acute bacterial sinusitis, chronic bronchitis, simple urinary tract infections, and acute otitis media. There may be an increased risk of tendon rupture in the shoulders, hands, and Achilles tendon while taking this drug, especially in elderly patients or those with renal impairment, and those taking corticosteroids should avoid co-administration. If experiencing pain or inflammatory symptoms, rest and avoid exercise, and discontinue use if symptoms are severe. Myasthenia gravis patients should be cautious as their symptoms may worsen with this drug. It should not be administered to patients with a history of hypersensitivity to this drug or similar antibiotics, growing adolescents under 18 years, pregnant or breastfeeding women, and patients with epilepsy. Caution is required for patients with severe renal impairment, central nervous system diseases, seizure history, those taking specific anti-inflammatory drugs or theophylline, elderly patients, diabetes patients, patients with certain genetic disorders, and those at risk for aneurysms or heart valve diseases. Various side effects may occur, including severe allergic reactions, neuropsychiatric disturbances, cardiac rhythm abnormalities, renal and liver function abnormalities, blood disorders, gastrointestinal disturbances, musculoskeletal pain or tendonitis, and severe skin reactions, so consultation with a physician is warranted in case of abnormal symptoms. This drug may cause photosensitivity, so avoid strong sunlight or artificial UV exposure. If dizziness or drowsiness occurs, avoid driving or operating machinery. Additionally, to prevent resistance, it is advisable to administer only after sensitivity testing and for the minimum required duration. There may be drug interactions, so caution is needed particularly when taken with anti-inflammatory drugs, antacids, iron supplements, hypoglycemic agents, or anticoagulants. Pregnant or breastfeeding women should not take this drug, and it should not be administered to children or adolescents in growth. Elderly patients may require dosage adjustments due to decreased renal function, and treatment should be stopped immediately if liver dysfunction symptoms appear. In case of overdose, central nervous system symptoms and cardiac abnormalities may occur, requiring immediate emergency treatment and ECG monitoring. This drug has been reported to cause joint anomalies in animal studies, so it is safer to avoid use in growing patients.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, sweating, pallor, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities with cough and fever, yellowing of the skin or eyes (jaundice), profound fatigue, sudden and severe headache, lightning headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

Insomnia, dizziness, headache, tremors, anxiety, depression, psychotic reactions (hallucinations, paranoia, irritability, delirium, disorientation, attention disturbances, nightmares), restlessness, confusion, visual and auditory disturbances, taste and smell disturbances, auditory hallucinations, sensory neuropathy, numbness, weakness, palpitations, QT interval prolongation, arrhythmia, increased BUN, increased serum creatinine, nausea, vomiting, abdominal discomfort, diarrhea, loss of appetite, abdominal pain,

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture. This helps maintain the drug's effectiveness for a longer period and prevents deterioration.

Appearance

White to pale yellow film-coated tablets

Package unit

50, 100, 200, 250, 300, 500, 1000 tablets