Hanmi Clarithromycin Tablets 250 mg

Adult dose

Adults: The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual treatment duration is 7～14 days. In patients with renal impairment whose creatinine clearance is 30mL/min or less, the dose should be reduced by half. That is, administer 250mg (potency) once daily, or 250mg (potency) twice daily for severe infections. Do not administer this drug to these patients for more than 14 days. Mycobacterial infections: Administer 500mg (potency) of this drug per dose twice daily. In this case, it should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this drug 3 times daily for 14 days together with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Child dose

Children 12 years and older: Same as adults For children under 12 years, use clarithromycin dry syrup.

This medication should not be administered to certain patients. For example, patients who are allergic to the ingredients contained in this medication or who have had hypersensitivity reactions to similar antibiotics should not use it. Additionally, patients with certain heart conditions or significantly impaired liver or kidney function, as well as pregnant or breastfeeding women, should not take this medication. Care should be taken in patients with heart disease as arrhythmias may occur while taking this medication. Patients with weak liver or kidney function may need dosage adjustments, so they should follow their doctor's directions. This medication can interact with various drugs, so it is essential to inform your doctor or pharmacist if you are taking other medications. Special caution is required when taken with certain heart-related medications, anticoagulants, hypoglycemic agents, and immunosuppressants. If you experience allergy symptoms or severe skin rashes, difficulty breathing, severe abdominal pain, diarrhea, hearing issues, dizziness, and other symptoms while taking this medication, discontinue use immediately and consult a healthcare professional. Long-term or high-dose use of this medication may cause hearing loss or tinnitus, so report if symptoms occur. Additionally, this medication should be used cautiously in children and the elderly, especially since sufficient studies have not been conducted in children under 12 years of age. When taking this medication, it is crucial to use it only for the necessary minimum period to prevent bacterial resistance. This medication may disrupt the intestinal bacterial balance, leading to diarrhea or colitis, so notify a healthcare professional immediately if persistent diarrhea occurs. During pregnancy or breastfeeding, this medication should be avoided as it may affect the fetus or infant. Overdose can result in gastrointestinal disturbances or mental symptoms, requiring immediate treatment. Finally, this medication should be stored away from direct sunlight at room temperature, and refrigeration should be avoided.

Shock, anaphylactic symptoms, difficulty breathing, convulsions, flushing, rashes, itching, hives, skin flushing, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, malaise, gas retention, diarrhea, oral mucosal erosion, upper abdominal pain, convulsive form, dry mouth, transient tooth discoloration, pancreatitis, increased amylase, taste disturbance, appetite loss, constipation, discoloration of stool, pseudomembranous colitis, hemorrhagic colitis, fever, cough, eosinophilia, eosinophilic lung infiltration, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucination, psychosis, depersonalization, convulsions, tremors, numbness, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, fatigue, headache, taste distortion, hearing loss, paresthesia, arthralgia, myalgia, olfactory disturbance, hearing impairment, cardiac arrest, atrial fibrillation, ECG QT prolongation, extrasystoles, palpitations, vasodilation, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, acute pancreatitis, tongue discoloration, tooth discoloration, rash, diaphoresis, vesicular dermatitis, annular rash, acne, Henoch-Schonlein purpura, acute generalized exanthematous pustulosis, muscle spasms, musculoskeletal rigidity, myopathy, elevated blood urea, nephritis, injection site phlebitis, injection site pain, injection site inflammation, fever, asthenia, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased INR, prolonged prothrombin time, abnormal urine color, changes in mental state, compulsive behaviors, hypokalemia, hypoxemia

This medication may be sensitive to air and light, so it should be stored in a sealed container, protected from light. Additionally, it is best to store it at room temperature between 1 and 30 degrees Celsius. Proper storage helps maintain the medication’s efficacy and safety.

Appearance

Yellow oval film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle