Itext Ceftriaxone Injection 1 gram (Ceftriaxone Sodium Hydrate)

Adult administration

For adults and children over 12 years, administer 1-2g (potency) of ceftriaxone once daily via intravenous or intramuscular injection. For infections caused by pathogens showing moderate sensitivity or severe diseases, the dose can be increased to 4g (potency) once daily. For gonorrhea treatment, a single intramuscular injection of 250mg (potency) is recommended. To prevent infections before and after surgery, administer 1-2g (potency) once 30-90 minutes before surgery.

Child administration

For newborns (within 14 days of birth), administer 20-50mg (potency) per Kg of body weight once daily without exceeding 50mg (potency). For infants, toddlers, and children (from 15 days to 12 years), administer 20

This medication must not be mixed or administered simultaneously with solutions containing calcium. Especially in newborns, deposits of calcium and this medication can have a fatal impact on the lungs or kidneys, so administration is prohibited. Patients with hypersensitivity to this medication or allergies to certain antibiotics and local anesthetics, premature infants, or newborns with jaundice or hypoalbuminemia should not use this medication. Patients who have previously had allergic reactions to this drug or similar antibiotics, those with allergic constitutions, or patients with severe renal disease should use it cautiously, and dosing adjustments may be necessary according to requirements. During the use of this drug, various side effects such as eosinophilia, hematologic disorders, diarrhea, rash, liver function abnormalities may occur, so if any abnormal symptoms appear, consult a doctor immediately. Regular monitoring of liver and kidney function, blood tests, etc., during administration is important, and if severe allergic reactions or shock symptoms occur, treatment should be stopped immediately and emergency measures should be taken. The safety of this drug during pregnancy has not been fully established; therefore, pregnant women should use it cautiously under the physician's judgment, and breastfeeding women should use it carefully as well. It is safest not to administer the drug to newborns and premature infants due to the risk of brain damage from increased bilirubin levels. Elderly patients may experience side effects more easily due to decreased physical function, so dosing and intervals should be adjusted, and careful observation is required. This drug may interact with other medications, so special care should be taken, especially when used in combination with diuretics, aminoglycoside antibiotics, vitamin K antagonists, etc., to closely monitor renal function and bleeding risks. Care should be taken with the preparation and infusion rate of the injection, and it must not be infused simultaneously with calcium-containing solutions. Additionally, the prepared solution should be used as soon as possible and stored at appropriate temperatures.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, high fever with severe rash, blisters, desquamation of the skin, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough + fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden, severe headache, thunderclap headache, seizures, confusion, vision disturbances, paralysis, urinary problems.

Mild side effects

• Eosinophilia
• leukopenia
• thrombocytopenia
• diarrhea
• rash
• increased liver enzymes
• dizziness
• bronchospasm
• soft stools
• nausea

This drug should be stored in a sealed container to protect it from air or moisture and kept in a cool room temperature away from direct sunlight.

Appearance

[For domestic use, for export 1] A vial filled with white to pale yellow crystalline powder [For export 2] A colorless vial filled with white to pale yellow crystalline powder

Package unit

1 vial (1g/vial X 1), 10 vials (1g/vial X 10)