Korea United Cephaclor Dry Syrup

Adult dosage

Adult: Administer 250 mg (based on potency) of cephaclor orally every 8 hours. In cases of severe infections (such as pneumonia) and those with low sensitivity, the dosage may be doubled. In the case of acute gonococcal urethritis, administer this drug 3 g along with 1 g of probenecid in a single dose.

Children's dosage

Pediatric: Administer 20 mg per kg body weight (based on potency) divided into doses every 8 hours. In cases of severe infections, otitis media, and infections with low sensitivity, a dosage of 40 mg per kg body weight can be administered.

This drug is an antibiotic that kills bacteria by binding to specific proteins and interfering with the synthesis of the bacterial cell wall. This drug should not be used in patients who have experienced severe allergic reactions or shock from this drug or cephalosporin antibiotics in the past. It also contains lactose, and should not be administered to patients with galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption. Caution should be exercised when using this drug in patients with a history of allergy to penicillin antibiotics or in individuals who frequently exhibit allergic symptoms like bronchial asthma, skin rashes, or urticaria. Patients with severely impaired kidney function, those who have difficulty swallowing orally, the elderly, and those in poor general condition should be monitored closely due to the risk of vitamin K deficiency. Patients with a history of gastrointestinal diseases, particularly colitis, also require caution. This drug can rarely cause shock or severe allergic reactions; therefore, symptoms should be closely observed during administration, and if abnormal signs appear, administration should be stopped immediately and appropriate treatment should be sought. Severe skin reactions may occur; therefore, if rashes, blisters, or skin peeling occur, immediate consultation with medical personnel is required. Blood abnormalities, liver function anomalies, and kidney function impairments may occur, necessitating regular tests, and administration should be stopped if any abnormalities are found. Gastrointestinal symptoms such as severe diarrhea, abdominal pain, or bloody stools should be immediately reported. Respiratory symptoms or central nervous system symptoms can also rarely occur; hence caution is advised. Prolonged use of this medication can lead to deficiencies in vitamin K and vitamin B complex, so symptoms should be carefully monitored. This drug should only be used for the minimum duration necessary to prevent antibiotic resistance, and prior to administration, a thorough check of allergy history and current status should be performed. Caution should be taken when used in conjunction with probenecid, nephrotoxic drugs, diuretics, and others as they may affect kidney function. Taking this medication with anticoagulants may increase the risk of bleeding, so regular checks of blood coagulation status are required. Using oral contraceptives concurrently may reduce their effectiveness, so it is advisable to use additional contraceptive methods. During pregnancy, safety has not been established, so it should only be administered if necessary, and caution is required for nursing mothers. Safety and efficacy have not been confirmed for infants under one month of age; therefore, it should be avoided in this population. Elderly patients may show adverse reactions more readily due to decreased physiological function, so dosage and administration intervals should be adjusted and closely monitored. Some urine tests may show false positive reactions while using this medication, so this should be considered when interpreting test results.

Serious side effects

Shock, anaphylactic symptoms (generalized rash, edema, difficulty breathing, angioedema, sensory disturbances, syncope, hypertension, vasodilation), Stevens-Johnson syndrome, toxic epidermal necrolysis, jaundice, acute renal failure, severe colitis (pseudomembranous colitis, etc.), interstitial pneumonia, eosinophilic pulmonary infiltration, altered consciousness, hallucinations, seizures, difficulty breathing

Mild side effects

• Rash
• urticaria
• erythema
• itching
• fever
• lymphadenopathy
• arthralgia
• serum sickness-like reaction
• agranulocytosis
• granulocytopenia

This drug is sensitive to light, so it should be stored in an opaque container. Furthermore, to maintain the drug's efficacy, it is important to store it at room temperature, specifically between 1 degree and 30 degrees.

Appearance

Pink powder for syrup

Package unit

150mL/bottle