Donghwa Cephaclor Capsule (Cephaclor Monohydrate)

Adult dose

For cephaclor monohydrate, administer 250mg (potency) orally every 8 hours. In cases of severe infections (such as pneumonia) and infections with low susceptibility, it can be administered at double the dosage. For acute gonococcal urethritis, administer this drug 3g combined with 1g of probenecid as a single dose.

Child dose

Administer 20mg (potency) per kg of body weight divided every 8 hours. In cases of severe infections, otitis media, and infections with low susceptibility, a dosage of 40mg (potency) per kg of body weight can be administered, with a maximum dosage of

This drug is an antibiotic that kills bacteria by interfering with the synthesis of certain bacteria's cell walls. This drug should not be used in patients who have experienced severe allergic reactions or shock from this drug or from similar classes of antibiotics in the past. It should also be used with caution in patients who are allergic to penicillin antibiotics, those with allergic conditions, those with severely impaired kidney function, those who have difficulty taking medications orally, elderly patients, and patients with gastrointestinal diseases. Severe allergic reactions or shock may occur when using this drug, so symptoms should be closely monitored and the administration should be stopped immediately if any abnormalities arise. Serious skin reactions may occur, so if rashes, blisters, or skin peeling occur, the use of the drug should be stopped immediately and a doctor should be consulted. Blood abnormalities, liver and kidney function impairments, gastrointestinal issues, respiratory symptoms, and central nervous system symptoms may rarely occur, so regular check-ups are needed, and any abnormalities should be reported immediately. This drug can disrupt the normal bacterial balance in the intestines, leading to infections such as stomatitis or candidiasis, so caution is necessary. Rare symptoms of bleeding tendency due to vitamin K deficiency or vitamin B complex deficiency may occur, so the patient's condition should be carefully monitored. This drug should be administered only for the minimum necessary duration after susceptibility testing to prevent the development of resistant strains, and interactions may occur when used in combination with other antibiotics, so doctor's instructions should be followed. Particularly, in patients with impaired kidney function, dosage and intervals should be adjusted, and attention should be paid as nephrotoxicity may increase when used with certain medications. Women who are pregnant or may become pregnant should only use this medication when the benefits outweigh the risks, as its safety has not been established, and caution is also necessary when breastfeeding. It is advisable not to use this drug in infants under 1 month of age as its safety and efficacy have not been confirmed. Elderly patients are more susceptible to adverse reactions owing to weakened body functions and may have a risk of bleeding due to vitamin K deficiency, so extra caution is required. False positive results may occur in urine tests while taking this medication, so this information should be disclosed during testing.

Serious side effects

Shock, anaphylactic symptoms (generalized flushing, swelling, difficulty breathing, angioedema, sensory disturbances, fainting, hypertension, vasodilation), hives, Stevens-Johnson syndrome, toxic epidermal necrolysis, agranulocytosis, pancytopenia, aplastic anemia, hemolytic anemia, liver abnormalities (jaundice, temporary hepatitis), reversible interstitial nephritis, acute renal failure, severe colitis, interstitial pneumonia, eosinophilic lung infiltrates, severe neurological symptoms (such as seizures)

Mild side effects

Serum sickness-like reactions (rash, erythema multiforme, arthritis, arthralgia, fever), rash, itching, fever, lymphadenopathy, blood system abnormalities (agranulocytosis, granulocytopenia, anemia, thrombocytopenia, eosinophilia, etc.), temporary hepatitis, elevated AST, ALT, ALP, nausea, vomiting, diarrhea, abdominal pain, gastrointestinal discomfort, heartburn, appetite loss, restlessness, anxiety, muscle tension, nervousness, insomnia, confusion, dizziness, hallucinations

This medication may be sensitive to air and humidity, so it must be stored in a tightly sealed container. The storage temperature should ideally be kept at room temperature between 1°C and 30°C. This will help maintain the effectiveness and safety of the medication.

Appearance

Capsule with purple upper and white lower containing a light yellow powder

Package unit

30 capsules/bottle, 100 capsules/bottle