Panaben Tablets (Ketotifen Fumarate)

Adult dose

Adults and children over 10 years: As ketotifen, 1 mg orally twice daily (morning and at dinner). If necessary, in children over 10 years, it can be administered up to 2 mg at a time. If sensitivity occurs, start treatment in the first week with 0.5 mg twice daily or 1 mg at bedtime, gradually increasing to 2 mg daily. Adjust based on age and symptoms.

Child dose

Children over 3 years: As ketotifen, 1 mg orally twice daily (morning and at dinner).

This medication should not be used by patients who have allergic reactions to this medication or its components, or who have had such experiences in the past. Individuals with epilepsy or seizure disorders, or a history of such conditions, should be cautious as seizures may occur when taking this medication. This medication cannot be used as a substitute for corticosteroid medications used in asthma treatment, and patients undergoing asthma treatment should not suddenly discontinue their existing treatment. Breastfeeding women are advised not to take this medication, and if unavoidable, should stop breastfeeding. Patients taking oral hypoglycemic agents may experience a decrease in platelet count when using this medication, so blood tests might be necessary. Patients with specific genetic issues such as fructose intolerance should avoid using this syrup formulation due to the maltitol component. When first taking this medication, symptoms such as drowsiness, dizziness, and dry mouth may occur but usually resolve naturally over time. Particular attention should be paid to children, as they may experience central nervous system symptoms such as excitability, insomnia, and nervousness, requiring careful observation. Caution is needed when performing tasks requiring concentration, such as driving or operating machinery, after taking this medication. If undergoing long-term steroid treatment, the dosage of steroids should be gradually reduced when taking this medication, with attention paid to adrenal insufficiency. This medication does not suppress already occurring seizures, which must be recognized. Patients with seasonal symptoms should begin taking this medication in advance of symptom onset and continue regularly during symptom duration. When discontinuing the medication, it should be gradually reduced over 2 to 4 weeks to minimize side effects. Caution is required when taken with sedatives, sleep aids, antihistamines, or alcohol, as their effects may be potentiated. Its safety during pregnancy has not been established, so it should only be used with caution when necessary, and breastfeeding women should avoid its use whenever possible. In case of overdose, symptoms such as drowsiness, confusion, seizures, and abnormal heart rhythms may occur, and immediate medical attention is required for appropriate treatment. This medication should be discontinued 3-5 days prior to allergy testing as it does not affect test results. Finally, keep this medication out of reach of children and store it in its original container to maintain its quality and ensure safe use.

Serious side effects

• Erythema multiforme
• Stevens-Johnson syndrome
• severe skin reactions
• hepatitis
• seizures
• urticaria

Mild side effects

• Cystitis
• weight gain
• excitability
• irritability
• insomnia
• nervousness
• dizziness
• sedation
• dry mouth
• increased liver enzymes

This medication should be stored in a tightly sealed container that is well-ventilated, and it is recommended to keep it at room temperature between 1 to 30 degrees Celsius. Doing so helps to maintain the medication's efficacy for a long time.

Appearance

White round tablets

Package unit

1000 tablets (bottle), 100 tablets (bottle), 30 tablets (bottle)