Shurosol Injection

Adult dosage

Generally, 500 mL is infused intravenously. Typically, the adult standard is set at 180 minutes for 500 mL. For central venous administration, this medication can be mixed with carbohydrate solutions and continuously infused into the central vein over a 24-hour period. Adjustments should be made appropriately based on age, symptoms, and weight.

This medication should be used only as directed by a physician. It should not be administered to patients with severe renal dysfunction or hyperazotemia. Patients with abnormal amino acid metabolism besides liver dysfunction should also not use this medication. It should not be administered to patients with metabolic disorders that hinder nitrogen utilization. Patients with wasting heart failure or pulmonary edema, as well as those with very low or no urine output, should not use this medication. If sodium or chloride ions are present, it should not be administered to patients with hypernatremia, hyperchloremia, or alkalosis. If magnesium ions are present, it should not be given to patients with heart block or myasthenia gravis. This medication should not be used in patients at risk of excessive fluid supply. In patients with severe acidosis or congestive and severe heart failure, it should be administered cautiously. Patients with edema due to sodium retention, hyperkalemia, or potassium retention should also be monitored closely. The dosage and rate of administration should be adjusted for patients with renal function issues. This medication contains sodium bisulfite, which may trigger allergic reactions or asthma attacks, so extra caution is required for asthmatic patients. If hypersensitivity reactions such as rashes occur during the use of this medication, administration should be stopped immediately. Occasionally, gastrointestinal symptoms such as nausea or vomiting may appear. Cardiac-related symptoms may include chest discomfort, palpitations, rapid heartbeat, and elevated blood pressure. Rapid administration of large doses may lead to acidosis, so caution is advised. Serious side effects such as chills, fever, headache, shortness of breath, and shock have been reported. When magnesium ions are present, peripheral vascular dilation symptoms may occur. Metabolic complications may include acidosis, alkalosis, hyperglycemia, diabetes, and electrolyte imbalances. In patients with impaired liver or kidney function, blood test values may change, necessitating regular monitoring. During large-scale administration, electrolyte balance should be carefully managed, as overdose may lead to metabolic alkalosis. Patients with a history of kidney disease, lung disease, or heart disease should take precautions to avoid fluid overload. Diabetic patients should frequently monitor their blood sugar levels. Patients with hyponatremia, liver, and kidney dysfunction should individually manage dosage adjustments and fluid and electrolyte status. This medication may interact with some other medications, especially tetracycline antibiotics, calcium salts, and vitamin B1 should be used with caution together. Its safety in pregnant women has not been established, and it should be administered only when the therapeutic benefit outweighs the risks. Children may have immature liver function, so it is necessary to maintain lower dosages and frequently check blood ammonia levels. Elderly patients may have decreased bodily functions, so administration should be slow, and the dosage should be reduced as necessary. This medication contains electrolytes, so great care must be taken with electrolyte balance during administration and rapid intravenous infusions should be avoided. The fluid should be warmed to body temperature before use and should be prepared in a sterile condition with sterilized injection devices. Before use, inspect the clarity and condition of the solution, and do not use it if abnormalities are present. This medication should not be administered to patients with a history of myocardial infarction.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, asthma attacks, respiratory distress, respiratory arrest, shock, bronchospasm, severe edema or urination difficulties accompanied by elevated blood pressure.

Mild side effects

• Rash
• nausea
• vomiting
• chest discomfort
• palpitations
• rapid pulse (tachycardia)
• elevated blood pressure
• chills
• fever
• headache

This medication should be stored in a sealed container to prevent air or moisture intrusion, and it is best to maintain the storage temperature between 1 and 30 degrees Celsius at room temperature. This helps ensure the medication's efficacy is safely maintained.

Appearance

The injection contains a colorless to slightly yellow transparent solution in a polypropylene aqueous injection bottle.

Package unit

250mL/box