Cefazolin Injection 1 Gram (Ceftriaxone Sodium Hydrate)

Adult administration

For adults and children over 12 years, administer 1–2g (potency) of ceftriaxone once daily via intravenous or intramuscular injection. For infections caused by severe pathogens or pathogens demonstrating moderate susceptibility, the dose may be increased up to 4g (potency) once daily.

Child administration

For neonates (within 14 days of birth), administer 20–50mg (potency) per Kg of body weight once daily, not exceeding 50mg (potency). For infants and children (from 15 days to 12 years old), administer 20–

This medication should not be mixed or administered simultaneously with solutions or drugs containing calcium. Especially in neonates, because calcium can react with this drug to form precipitates, leading to serious side effects, it should not be administered under any circumstances. This drug should not be given to patients with allergies to it or those who have had hypersensitivity reactions to cephalosporins or penicillin antibiotics. Also, patients who are hypersensitive to lidocaine should be cautious. This medication should not be administered to premature infants, infants with jaundice, or neonates with problems in bilirubin binding in the blood. It can displace bilirubin from serum albumin, increasing the risk of encephalopathy. When administering this medication, various side effects, including allergic reactions, blood abnormalities, gastrointestinal problems, liver function abnormalities, and kidney function abnormalities, may occur, so patients must be monitored closely. If severe allergic reactions or shock symptoms appear, administration should be stopped immediately, and emergency treatment should be implemented. During administration, it is important to regularly check liver and kidney functions and conduct blood tests to identify any abnormalities. This medication may increase the risk of bleeding due to vitamin K deficiency, so vitamin K supplementation may be necessary. Elderly patients or those with poor kidney function should have their dosage and administration intervals adjusted. Caution is advised when driving or operating machinery due to potential side effects like dizziness. This drug may interact with other medications; therefore, careful monitoring is necessary, especially when used in conjunction with diuretics, aminoglycoside antibiotics, and vitamin K antagonists. Women who are pregnant or breastfeeding should use this medication only when the benefits of treatment outweigh the risks to the fetus or neonate. The prepared solution should be used as soon as possible, and it is safe to use within a certain time frame when stored.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe skin adverse reactions (severe rash, blisters, skin peeling, pain in mucous membranes of the mouth/eyes), respiratory issues (shortness of breath or difficulty breathing, asthma attacks, abnormal breathing accompanied by cough+fever), liver abnormalities (yellowing of the skin or eyes, generalized malaise), severe neurological symptoms (sudden and very severe

Mild side effects

• Eosinophilia
• leukopenia
• thrombocytopenia
• diarrhea
• rash
• increased liver enzymes
• headache
• dizziness
• bronchospasm
• loose stools

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture and should be stored in a cool room away from direct sunlight. Proper storage will help maintain the efficacy of the drug for a longer period.

Appearance

A vial filled with white to slightly yellow powder

Package unit

[Domestic] 10 vials/box (1g (potency)/vial) [Export] 10 vials/box (1g (potency)/vial)