Albozen Ceftriaxone Sodium Hydrate Injection 1 Gram

Adult administration

As ceftriaxone, administer 1–2 g (potency) once daily intravenously or intramuscularly. For infections caused by severe disease or moderately sensitive pathogens, the dose may be increased to 4 g (potency) once daily. For treatment of gonorrhea, a single intramuscular injection of 250 mg (potency) is recommended. To prevent infections before and after surgery, a single dose of 1–2 g (potency) is given 30–90 minutes prior to the surgery. In cases of end-stage renal impairment, the dosage must not exceed 2g (potency) daily.

Child administration

For infants (under 14 days old), administer 20–50 mg (potency) per Kg of body weight once daily, not exceeding 50 mg (potency). For infants and children (15 days to 12 years), administer 20–

This medication should not be mixed or administered simultaneously with calcium-containing solutions or drugs. Particularly in newborns, mixing this drug with calcium solutions can lead to precipitate formation and poses a serious risk of adverse effects, thus it should be avoided. Patients with a history of allergic reactions to this drug or hypersensitivity to cephalosporin or penicillin antibiotics should not use this medication. Additionally, premature infants or newborns with problems in bilirubin binding should also not be administered this drug. Patients who have previously experienced allergic reactions to medications, asthma, rash, or similar symptoms should be particularly cautious when administering this medication. Patients with impaired renal function may require dose adjustments. Moreover, due to the risk of vitamin K deficiency, blood coagulation status should be monitored regularly. Using this medication may result in side effects such as diarrhea, rash, liver function abnormalities, and decreased blood cell counts; in severe cases, acute allergic reactions such as anaphylaxis may occur. If symptoms appear, treatment should be stopped immediately and medical personnel should be notified. During treatment, regular assessments of liver and kidney function, as well as blood tests, should be conducted, particularly since high-dose administration may lead to precipitate formation in the gallbladder. There are no specific antidotes for overdose, and treatment should be based on symptoms. The safety of this medication during pregnancy has not been established, so pregnant women should consult a physician before use, and it should be administered with caution in nursing mothers. Caution is required when driving or operating machinery, as side effects such as dizziness may occur. Additionally, this medication may interact with other cephalosporin antibiotics, diuretics, and aminoglycoside antibiotics, so if there are any concomitant medications, it is essential to inform a doctor or pharmacist. Lastly, it is crucial to administer this medication only for the duration necessary according to sensitivity testing, and to consult medical personnel promptly if unusual symptoms arise during treatment.

Serious side effects

Urticaria, severe swelling (edema), cold sweats, difficulty in breathing, severe allergic reactions, high fever with severe rash, blisters, skin peeling, pain in oral/eye mucous membranes, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice), sudden and very severe headaches, lightning headaches, seizures

Mild side effects

• Eosinophilia
• leukopenia
• thrombocytopenia
• diarrhea
• rash
• increased liver enzymes
• genital fungal infections
• pseudomembranous colitis
• agranulocytosis
• anemia

This medication should be stored in a sealed container to prevent exposure to air or moisture, and it is recommended to keep it away from direct sunlight and at normal room temperature.

Appearance

A colorless transparent vial filled with white to pale yellow crystalline powder

Package unit

10 vials (1g/vial X 10)