Nutamin Injection

Adult dosage

In general, administer 500 mL as a drip infusion. The infusion rate is usually adjusted based on a standard of more than 180 minutes for 500 mL in adults. When administering via central venous catheter, 500 mL is mixed with dextrose solution and continuously infused over 24 hours into the central vein. Adjust as appropriate based on age, symptoms, and body weight.

This drug should only be used according to a doctor's instructions and should not be taken based on personal judgment. It should not be used in patients with severely impaired kidney function or high blood nitrogen levels. Even in the absence of liver dysfunction, it is safer not to administer this drug to patients with amino acid metabolism abnormalities. This drug is also not suitable for patients with metabolic disorders involving nitrogen utilization issues, severe heart failure, or pulmonary edema. Patients with very low or no urine output, and those with abnormally high sodium or chloride levels should not be administered this drug. If magnesium is included, it is important not to administer it to patients with heart block or severe myasthenia gravis. It is safer not to use this drug in patients who are in a state of excessive fluid supply or have a history of myocardial infarction. Patients with severe acidosis, heart failure, edema, or electrolyte imbalances should be used cautiously, especially those with sulfur dioxide allergies or asthma. This drug can rarely cause hypersensitivity reactions such as skin rashes, so it should be discontinued immediately if symptoms occur. Gastrointestinal symptoms such as nausea, vomiting, or symptoms like rapid heartbeat may also occur. When administered in large amounts quickly, metabolic acidosis may occur, so caution is advised. In addition, serious symptoms such as chills, fever, headache, and difficulty breathing may occur. If any abnormal symptoms arise, consultation with medical personnel is necessary. If magnesium is included, the blood vessels may dilate, so attention should be paid to changes in blood pressure. Various metabolic abnormalities such as metabolic acidosis, electrolyte imbalance, and blood sugar changes can occur, so regular blood tests are necessary. Patients with poor liver or kidney function should be carefully monitored as specific blood levels may rise. In cases of large volume administration, careful adjustment is required to maintain electrolyte balance, especially to avoid excessive fluid supply in patients with kidney, lung, or heart diseases. Diabetic patients should regularly check blood sugar levels while using this drug. It can interact with other drugs, so caution is required, especially when used with certain antibiotics or calcium preparations. The safety of this drug has not been established during pregnancy, and it should only be used when the benefits outweigh the risks. In children, liver function may be immature, so concentrations should be lowered, and blood ammonia levels should be measured frequently. The elderly may have decreased physical function, so the administration rate should be slow and the dosage adjusted. When administering, check for electrolyte content, avoid rapid infusion, and use the drug at body temperature. Always prepare in a sterile condition and be careful with the sterilization of the administration equipment. If the solution is cloudy or discolored, it should not be used, and storage should be limited to within 24 hours in a refrigerator. Care should be taken to ensure that the drug solution is not contaminated before the packaging is opened, and damaged packaging should not be used.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe allergic reactions, dyspnea, respiratory arrest, shock, bronchospasm, urinary tract spasms, shortness of breath or difficulty breathing, asthma attacks, liver failure, and kidney failure symptoms, extreme lethargy, sudden and severe headache, seizures, consciousness disturbance, visual disturbances, paralysis, markedly reduced urine output, severe generalized swelling with increased blood pressure

Mild side effects

• Rash
• nausea
• vomiting
• chest discomfort
• palpitations
• tachycardia
• increased blood pressure
• acidosis
• chills
• fever

This drug should be stored in a sealed container to prevent exposure to air, avoiding direct sunlight, and should be stored at room temperature. This helps maintain the drug's effectiveness for a longer time.

Appearance

A colorless to pale yellow transparent solution contained in a polypropylene aqueous injection container.

Package unit

100 milliliters, 250 milliliters