Saeronamin Injection

Adult dosage

Generally, as total amino acids, 1.5 g per day per kg of body weight (equivalent to 1300 mL per day for a person weighing 70 kg) should be administered as an intravenous drip at the maximum dosage. The infusion rate should be a maximum of 1.25 mL per kg of body weight over 60 minutes.

This medication must be used under the direction of a physician, as arbitrary use may pose risks. It should not be administered to patients with poor kidney function, high blood nitrogen levels, liver dysfunction, and those with nitrogen metabolism issues. Patients with poor cardiac function or lung issues, very low or no urine output, acidosis, and those with excessive fluid retention should also avoid using this medication. Patients with a history of myocardial infarction, hyponatremia, shock, or hypoxia should also not be administered this drug. Patients with edema or a history of kidney and lung diseases, severe heart disease, and diabetes should use this medication cautiously, as there are risks of allergic reactions or asthma attacks. This drug may rarely cause side effects such as rash, nausea, vomiting, chest discomfort, palpitations, and elevated blood pressure. Rapid large dosing may lead to acidosis, and serious symptoms such as chills, fever, headache, difficulty breathing, and shock may occasionally occur. Additionally, various metabolic abnormalities such as metabolic acidosis, hypophosphatemia, hyperglycemia, and electrolyte imbalances may arise, requiring regular blood tests and status monitoring. For patients with renal failure, care should be taken as blood urea nitrogen levels may rise. This drug may interact with other medications, particularly reducing its effectiveness when used with tetracycline antibiotics. Pregnant or breastfeeding women should carefully consider the risks and benefits when using this medication. In children, due to potential immaturity in liver function, the concentration should be adjusted lower, and blood ammonia levels should be monitored frequently. Elderly patients may have diminished body functions, thus the infusion rate should be slowed down and dosages adjusted. This medication contains electrolytes, so attention should be paid to electrolyte balance during large doses, and if given too quickly, chills or vomiting may occur. Before administration, the solution should be brought to roughly body temperature, and it should be prepared and managed in a sterile state to reduce the risk of infection. Do not use if the solution has changed color or has become cloudy, and it is advisable to restrict storage to within 24 hours. Finally, it is safest not to use the product if the packaging or container is damaged.

Serious side effects

Breathing difficulties, respiratory arrest, shock, bronchospasm, and urinary tract spasm may occasionally occur.

Mild side effects

• Rash may occur rarely.
• Occasional symptoms of nausea and vomiting may appear.
• Symptoms such as chest discomfort, palpitations, rapid heartbeat, and elevated blood pressure may be present.
• Acidosis may occur with rapid large doses.
• Occasional chills, fever, and headache may appear.
• Metabolic acidosis, hypophosphatemia, alkalosis, hyperglycemia, diabetes, osmotic diuresis and dehydration, rebound hypoglycemia, elevated liver enzymes, vitamin deficiencies or excesses,

This medication should be stored in a sealed container to avoid exposure to air and is best kept at room temperature between 1 degree and 30 degrees Celsius. Storing it this way helps maintain the effectiveness of the medication and prevents degradation.

Appearance

A colorless to pale yellow transparent solution packaged in a colorless transparent glass container or a polypropylene aqueous injection container.

Package unit

250mL/bottle, 250mL/bag