Medication info
Iyeon Clarithromycin Tablets

Iyeon Clarithromycin Tablets

Prescription medicationTabletOral
Ingredient · strength
Clarithromycin›250mg / 1 tablet
Manufacturer / importer
Iyeon Pharmaceutical Co., Ltd.
Appearance
Yellow oval film-coated tablets
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 199500174 · Notified 1995.12.28 · Insurance code 658601540

Summary

Main use
Treatment of infections (respiratory, skin, and mycobacterial infections); Helicobacter pylori eradication for duodenal ulcers
Who takes it
Adults · Children
Adult dose
○ Adults: The usual dose is 250mg (potency) of clarithromycin per administration, twice daily. For severe infections, administer 500mg (potency) per dose twice daily. The usual duration of treatment is 7~14 days. In patients with renal failure and a creatinine clearance of 30mL/min or less, reduce the dose by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) per dose twice daily. Do not administer to these patients for more than 14 days. ○ Mycobacterial infections: Administer 500mg (potency) of this medicine per dose twice daily. In this case, it must be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, or rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcer: Administer 500mg (potency) of this medicine 3 times daily with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (days 1~14), and omeprazole 40mg once daily for 28 days (days 1~28).
Child dose
○ Children 12 years and older: Same as adults. ○ For children under 12 years, use clarithromycin dry syrup.

Ingredients

Manufacturer
Iyeon Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of infections (respiratory, skin, and mycobacterial infections); Helicobacter pylori eradication for duodenal ulcers

  • Bronchitis
  • pneumonia
  • pharyngitis
  • sinusitis
  • skin and soft tissue infections
  • mycobacterial infections
  • duodenal ulcers
View approved original text

This medication is effective against a variety of bacteria. It is used for lower respiratory tract infections like bronchitis and pneumonia, as well as upper respiratory tract infections such as pharyngitis and sinusitis. It also helps in the treatment of skin and soft tissue infections, and is effective against infections caused by Mycobacterium avium and Mycobacterium intracellular. Additionally, it is used to eradicate Helicobacter pylori, which causes duodenal ulcers. This medication aids in treating various bacterial infections.

How to take

Adult dose

○ Adults: The usual dose is 250mg (potency) of clarithromycin per administration, twice daily. For severe infections, administer 500mg (potency) per dose twice daily. The usual duration of treatment is 7~14 days. In patients with renal failure and a creatinine clearance of 30mL/min or less, reduce the dose by half: 250mg (potency) once daily, or, for severe infections, 250mg (potency) per dose twice daily. Do not administer to these patients for more than 14 days. ○ Mycobacterial infections: Administer 500mg (potency) of this medicine per dose twice daily. In this case, it must be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, or rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcer: Administer 500mg (potency) of this medicine 3 times daily with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (days 1~14), and omeprazole 40mg once daily for 28 days (days 1~28).

Child dose

○ Children 12 years and older: Same as adults. ○ For children under 12 years, use clarithromycin dry syrup.

Precautions

This medication should not be used in patients who are allergic to specific ingredients or have had hypersensitivity reactions to macrolide antibiotics. Patients with abnormal heart rhythms or severely impaired liver or kidney function should use this medication cautiously. It is safe to avoid this medication during pregnancy and breastfeeding. While taking this medication, there may rarely be severe allergic reactions, skin rashes, gastrointestinal disturbances, liver function abnormalities, or kidney issues; if any unusual symptoms occur, consult a doctor immediately. Interactions may occur when taken with other medications, especially those affecting the heart, drugs metabolized by the liver, hypoglycemic agents, and anticoagulants, so caution is advised when taken in combination. If persistent diarrhea or abdominal pain occurs during treatment, it may indicate serious intestinal conditions such as pseudomembranous colitis; inform your healthcare provider immediately. Dose adjustments may be necessary in patients with compromised liver and kidney function, and elderly patients should also be administered cautiously. Prolonged or high-dose use may lead to hearing loss or tinnitus; inform a doctor if these symptoms occur. This medication may cause dizziness or confusion while driving or operating machinery, so caution is advised. In cases of overdose, gastrointestinal disturbances or psychiatric symptoms may arise, and you should seek appropriate treatment at a medical facility immediately.

Side effects

  • Shock
  • anaphylactic symptoms
  • difficulty breathing
  • convulsions
  • flushing
  • rash
  • itching
  • hives
  • skin reddening
  • angioedema
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  • joint swelling
  • drug rash
  • abdominal bloating
  • nausea
  • vomiting
  • dyspepsia
  • abdominal pain
  • discomfort
  • flatulence
  • diarrhea
  • oral mucosal erosion
  • epigastric pain
  • thirst
  • tooth discoloration
  • pancreatitis
  • increased amylase
  • dysgeusia
  • anorexia
  • constipation
  • stool discoloration
  • pseudomembranous colitis
  • hemorrhagic colitis
  • fever
  • cough
  • abnormal chest X-ray
  • eosinophilia
  • eosinophilic lung infiltration
  • interstitial pneumonia
  • chronic bronchitis
  • acute maxillary sinusitis
  • thrombocytopenia
  • pancytopenia
  • hemolytic anemia
  • leukopenia
  • agranulocytosis
  • dizziness
  • depression
  • loss of taste
  • loss of smell
  • anxiety
  • insomnia
  • nightmares
  • tinnitus
  • confusion
  • orientation disturbance
  • hallucination
  • psychosis
  • depersonalization
  • tremors
  • numbness
  • Stevens-Johnson syndrome
  • toxic epidermal necrolysis
  • allergic purpura
  • drug rash
  • jaundice
  • hepatocellular hepatitis
  • cholestatic hepatitis
  • increased liver enzymes
  • liver dysfunction
  • liver failure
  • fulminant hepatitis
  • elevated AST
  • elevated ALT
  • elevated γ-GTP
  • elevated LDH
  • elevated ALP
  • increased total bilirubin
  • elevated serum creatinine
  • elevated BUN
  • interstitial nephritis
  • renal failure
  • rhabdomyolysis
  • glossitis
  • stomatitis
  • oral candidiasis
  • QT prolongation
  • ventricular tachycardia
  • Torsades de pointes
  • malaise
  • headache
  • dysgeusia
  • hearing loss
  • paresthesia
  • arthralgia
  • myalgia
  • olfactory dysfunction
  • auditory dysfunction
  • hypoglycemia
  • tinnitus
  • hearing impairment
  • purpuric rash
  • intravenous site phlebitis
  • intravenous site pain
  • intravenous site inflammation
  • fever
  • asthenia
  • chest pain
  • chills
  • fatigue
  • abnormal albumin-globulin ratio
  • elevated serum alkaline phosphatase
  • elevated serum lactate dehydrogenase
  • increased international normalized ratio
  • prolonged prothrombin time
  • abnormal urine color

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air and moisture. Avoid direct sunlight and store in a dry place at room temperature between 1 to 30 degrees Celsius.

Appearance and packaging

Appearance

Yellow oval film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.