BSSPLUS Solution

Adult use

After removing the blue caps from Component 1 (480mL) and Component 2 (20mL), clean and disinfect the rubber stopper with sterile alcohol swabs. Under sterile conditions, transfer 20mL of the solution from the Component 2 vial to the Component 1 bottle, gently shaking to mix well. Seal the bottle with a sterile cap and label it with the mixing date, time, and name of the patient who will use it. The irrigating solution is used according to the specified method based on the type of surgery.

This medication should not be used by patients who have allergic reactions to its components. Special caution is needed when used by diabetic patients or patients with damaged corneal endothelial cells. During use, corneal edema, reduced corneal function, or post-surgical inflammatory reactions may occur, so if any abnormal symptoms appear, medical consultation should be sought immediately. Ocular-related side effects such as increased intraocular pressure have been reported with this medication, so regular ophthalmic exams may be necessary. To minimize damage to the cornea and other ocular tissues during surgery, the prescribed dosage and method should be strictly adhered to. The infusion set used with this medication contains natural rubber latex, so caution is required for individuals with latex allergies. When diabetic patients undergo vitrectomy while using this medication, changes in the lens may occur, so it should be used with caution. Post-surgery, corneal opacity or edema may develop, so appropriate management is necessary to prevent these complications. Temporary blurred vision may occur after surgery; therefore, driving or operating machinery should be avoided until vision is fully restored. There is insufficient safety data regarding the use of this medication in pregnant women; however, as it contains components present in the eye and has no pharmacological action, it is expected to have minimal reproductive effects. Though insufficient data exists on whether this medication is excreted in breast milk, it is projected to have little impact on neonates due to its lack of pharmacological activity. In pediatric patients, similar safety has been observed relative to adults. This medication should only be used as an irrigating solution during ophthalmic surgery and must not be administered intravenously. Each package is intended for use by a single patient only, and any remaining contents should be discarded. As it does not contain preservatives, it cannot be reused once opened, and it should not be used if the solution is cloudy or not in a vacuum-sealed state. It should be used only after Components 1 and 2 are completely mixed, and it should not be used if the vacuum state is not maintained. If the mixed solution is discolored or contains precipitates, it should not be used, and it must be discarded if not used within 6 hours after mixing. Do not mix with other substances, as this may cause damage to the ocular tissues.

Mild side effects

• Corneal edema
• corneal dysfunction
• post-surgical inflammatory reactions
• loss of corneal endothelial cells
• corneal swelling
• increased intraocular pressure
• temporary blurred vision

This medication should be stored at a cool temperature between 2 degrees and 25 degrees Celsius, and it is important to keep it sealed in a container that allows no air to enter. This will help maintain the effectiveness of the medication and prevent degradation.

Appearance

Component 1: A colorless, transparent solution in a colorless, transparent bottle. Component 2: A colorless, transparent solution in a colorless, transparent vial.

Package unit

Component 1 - 480 milliliters/bottle, Component 2 - 20 milliliters/vial