Rofshin Tablet 250mg (Ciprofloxacin Hydrochloride Hydrate)

Adult dose

For the average adult, ciprofloxacin is administered orally at a dose of 250 to 500 mg twice daily between meals. In the case of severe complex infections, the dose may be increased to 750 mg twice daily. Treatment for acute infections generally lasts for 5 to 10 days, and even after symptoms resolve, it is administered for at least 3 additional days. Dosage adjustments are based on creatinine clearance for patients with renal impairment, with those having over 50 mL/min receiving standard dosage.

This medication can cause serious side effects, including tendinitis or tendon rupture, peripheral neuropathy, central nervous system abnormal reactions, and exacerbation of myasthenia gravis. Special caution should be taken as the risk of tendinitis or tendon rupture is higher in elderly patients or those with renal impairment or when taken with corticosteroids. Patients with severe myasthenia gravis should not be treated with this medication as it may worsen symptoms. Women who are pregnant or could become pregnant, nursing mothers, adolescents under 18 years of age, patients with a history of epilepsy, and those who have had hypersensitivity reactions to this drug or similar drugs should not use it. Additionally, caution is required for patients taking certain medications, as the risk of side effects may increase when taking drugs like tizanidine or ketoprofen. This medication should be used with caution in patients with severe renal impairment, those with a history of seizure disorders, elderly people, and patients with central nervous system conditions. Side effects like altered glucose levels, liver function abnormalities, neurological issues, and cardiovascular issues may also occur, requiring careful monitoring. If any symptoms such as rash, muscle pain, visual changes, severe diarrhea, or changes in mental status occur during treatment, immediate consultation with a physician is necessary. Furthermore, this drug may interact with various other medications, so patients should inform healthcare professionals of any other medications they are taking. The use of this medication is not recommended during pregnancy or lactation, especially during lactation, breastfeeding should be stopped or the medication avoided. Its safety has not been established for children and growing adolescents, so it is best not to use it in these populations. Elderly individuals should use this medication cautiously due to the potential for prolonged retention in the body due to decreased renal function, necessitating adjustments to dosage and administration intervals. Overdosage poses a risk of renal damage, so prescribed doses should be strictly adhered to. This medication should be stored away from direct sunlight and ultraviolet light and kept out of reach of children.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blistering, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, cough with febrile respiratory distress, yellowing of the skin or eyes (jaundice), extreme fatigue, sudden and severe headache, lightning headache, seizures, confusion, visual disturbances, paralysis, urination changes.

Mild side effects

• Headache
• dizziness
• sleep disorders
• taste disorders
• insomnia
• sensory disturbances
• sensory loss
• loss of taste
• tremors
• drowsiness

This medication should be stored in a tightly sealed container to prevent air exposure, and it is best kept at room temperature between 1°C and 30°C. This storage method helps maintain the medication's effectiveness and prevents degradation.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle