Medication info

Taeguk Cimetidine Tablets

Prescription medicationTabletExpired
Ingredient · strength
Cimetidine›200mg / 1 tablet
Manufacturer / importer
태극제약(주)
Appearance
Light green round tablets
Packaging
1000 tablets/bottle
Approval status
Expired

MFDS item code 199301085 · Notified 1993.06.16

This product's status changed to Expired on 2025.04.01. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of gastric and duodenal ulcers and gastroesophageal reflux disease, improvement of gastric mucosal lesions
Who uses it
Adults · Children
Adult dosage
Administer 400 mg of cimetidine orally twice daily (in the morning and at bedtime) or 800 mg once daily (at bedtime). Additionally, administer 300 mg orally four times a day (after meals and at bedtime). The dose can be increased up to 1.6 g daily (400 mg four times a day after meals and at bedtime). For improving gastric mucosal lesions during acute exacerbations of acute gastritis and chronic gastritis, administer 200 mg twice daily or 400 mg once daily.
Children's dosage
Administer 20-40 mg per kg of body weight daily in divided doses.

Ingredients

Manufacturer
태극제약(주)

Efficacy & effects

Treatment of gastric and duodenal ulcers and gastroesophageal reflux disease, improvement of gastric mucosal lesions

  • Gastric ulcers
  • duodenal ulcers
  • gastroesophageal reflux disease
  • recurrent ulcers
  • anastomotic ulcers
  • Zollinger-Ellison syndrome
  • gastric mucosal lesions
  • erosion
  • bleeding
  • erythema
  • swelling
  • acute gastritis
View approved original text

This medication is used for various gastrointestinal disorders such as gastric and duodenal ulcers, gastroesophageal reflux disease, recurrent ulcers, anastomotic ulcers, and Zollinger-Ellison syndrome. It also helps to improve gastric mucosal lesions (erosion, bleeding, erythema, swelling) that occur during acute exacerbations of acute and chronic gastritis. This medication is effective in protecting the gastric mucosa and relieving symptoms, thereby improving the quality of life for patients. Overall, it is used to treat various ulcers and inflammatory conditions related to the gastrointestinal tract.

Dosage and Administration

Adult dosage

Administer 400 mg of cimetidine orally twice daily (in the morning and at bedtime) or 800 mg once daily (at bedtime). Additionally, administer 300 mg orally four times a day (after meals and at bedtime). The dose can be increased up to 1.6 g daily (400 mg four times a day after meals and at bedtime). For improving gastric mucosal lesions during acute exacerbations of acute gastritis and chronic gastritis, administer 200 mg twice daily or 400 mg once daily.

Children's dosage

Administer 20-40 mg per kg of body weight daily in divided doses.

Precautions

This medication contains cimetidine and should not be used in certain patients. Patients who are allergic to cimetidine or other components of this medication or have experienced hypersensitivity reactions should not take this medication. Additionally, patients taking dofetilide should avoid this medication due to an increased risk of cardiac arrhythmias. This medication contains lactose, so patients with lactose intolerance or certain genetic metabolic disorders should not take it. Patients with kidney or liver function problems should adjust the dosage or increase the interval when using this medication, and patients receiving hemodialysis should take it after dialysis. Patients with a history of drug hypersensitivity, elderly patients, and children under 19 should also use it cautiously. This medication may mask symptoms of gastric cancer, so it is safer to take it after confirming the malignancy. Patients with gastric and duodenal ulcers due to Helicobacter pylori infection should undergo bacterial eradication treatment concurrently. Additionally, caution is required for those with allergies to Yellow No. 4 (Tartrazine) included in this medication. During treatment, side effects such as decreased blood cell counts, liver function abnormalities, kidney problems, allergic reactions, gynecomastia, excessive milk secretion, increased vaginal discharge, erectile dysfunction, abdominal bloating, constipation, diarrhea, headache, dizziness, limb numbness, drowsiness, hypochondriacal symptoms, weakness, bradycardia, and tachycardia may occur rarely. Especially if there are symptoms of systemic malaise, fever, or bleeding, immediate medical attention should be sought for examination. This medication should be used at the minimum effective dose, and if ineffective, it is advisable to switch to another treatment method. Patients with a history of peptic ulcers, elderly patients, and those with weakened immune systems may have an increased risk of infections, so regular observation is necessary. Additionally, there may be interaction potential with other medications like anticoagulants, so consulting healthcare professionals for appropriate adjustments is necessary. Pregnant women and nursing mothers should use this medication cautiously, as its safety has not been established, and nursing should be discontinued during use. There is limited experience with pediatric use, so it should only be administered in special cases. Elderly individuals may require adjustment of dosage and intervals due to decreased kidney function, which can increase drug concentration. In cases of overdose, severe symptoms such as respiratory depression may occur; therefore, immediate medical evaluation and appropriate treatment are essential. Finally, this medication should be stored out of the reach of children, and it is safe not to transfer it to other containers.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, peeling skin, pain in the mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), profound lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urinary issues

Mild side effects

  • Leukopenia
  • agranulocytosis
  • thrombocytopenia
  • pancytopenia
  • aplastic anemia
  • immune hemolytic anemia
  • hepatitis
  • elevated AST/ALT
  • hepatic fibrosis
  • interstitial seizures
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  • acute renal failure
  • interstitial nephritis
  • urinary retention
  • elevated BUN
  • gynecomastia
  • galactorrhea
  • increased vaginal discharge
  • erectile dysfunction
  • abdominal bloating
  • constipation
  • diarrhea
  • headache
  • dizziness
  • limb numbness
  • drowsiness
  • hypochondriacal symptoms
  • weakness
  • bradycardia
  • tachycardia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is advisable to maintain the storage temperature between 1 and 30 degrees Celsius at room temperature. This will help keep the medication's efficacy and safety for a longer period.

Appearance and packaging

Appearance

Light green round tablets

Package unit

1000 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.