Innoen 10% Glucose Injection

Adult administration

Administer 20 to 500 mL intravenously once. The intravenous infusion rate as glucose should not exceed 0.5 g/kg per hour. An appropriate amount should be used for the dilution of the injection. Adjust according to age and symptoms.

Caution is required when using this medication in ampoule injection form, as glass fragments may be introduced when cutting the glass bottle. Special caution should be taken when using it in children and the elderly. Patients receiving this medication intravenously may experience increased consumption of Vitamin B1, thus increasing the risk of sudden vitamin deficiency. This medication should not be administered to patients with specific conditions. For example, patients with storage dehydration, fluid overload, hyperglycemia, acidosis, hypokalemia, hyperosmolar coma, glucose intolerance, anuria, hepatic coma, etc., should not use this medication. Additionally, this form of medication should not be administered to patients with spinal hemorrhage, intracranial hemorrhage, or tremulous delirium. Patients with a tendency for potassium, phosphate, magnesium deficiency, or hyponatremia, diabetes insipidus, renal failure, heart failure, severe malnutrition, thiamine deficiency, sepsis, serious trauma, severe dehydration or shock, blood dilution, chronic uremia, and diabetes should be administered this medication cautiously. Rapidly administering large amounts can lead to electrolyte imbalances, so caution is necessary. Exceeding the recommended dosage may lead to increased levels of bilirubin and lactate. Hypokalemia, hyperosmolar coma, acidosis, dehydration, hyperosmolarity, and polyuria may occur, while intravenous administration may lead to fluid overload or electrolyte imbalances, congestion, and pulmonary edema. Diabetes intolerant patients may be at risk for hyperglycemia and renal loss. Heat, phlebitis, thrombosis, pain, and uremia may occur at the injection site. Prolonged administration may affect insulin secretion, and insulin should be administered if necessary. Patients post-surgery or trauma with glucose intolerance should use a 5% solution while monitoring blood sugar levels during treatment. Electrolyte serum testing, monitoring fluid balance and blood glucose concentration are essential, with careful observation of patient conditions and blood potassium and phosphate levels is required. During pregnancy, the safety of this medication has not been established, and it should only be administered if the therapeutic benefits outweigh the risks to the fetus. When administered during delivery, both the mother and newborn are at risk of hyperglycemia and metabolic acidosis, so careful consideration is necessary. Neonates, especially premature or low-birth-weight infants, are at higher risk for hypoglycemia and hyperglycemia, and blood sugar must be monitored closely, as hypoglycemia can lead to serious brain damage. Elderly patients require special caution when using this medication due to decreased physical function. Overdosing may lead to hyperglycemia or diabetes, which must be managed with insulin. Subcutaneous injections should be avoided due to the risk of circulatory failure caused by electrolyte movement in plasma and due to severe local irritation. Use immediately after opening, and any remaining solution should be discarded, taking care to avoid infection during administration. It is advisable to warm the medication to body temperature before use, and caution should be exercised when administering hypertonic solutions due to the risk of thrombophlebitis. Rapidly discontinuing high-concentration solutions can cause hypoglycemia, so caution is advised. Do not administer simultaneously with blood, and ensure careful observation due to the risk of chemical or physical interactions when mixed with other medications. Interaction with containers and stoppers should also be cautious, and mixed medications should be used immediately to avoid air embolism risks.

Mild side effects

Hypokalemia, hyperosmolar coma, acidosis, dehydration, hyperosmolarity, polyuria accompanied by glucose detection, fluid or solute overload, fluid-electrolyte imbalance, congestion, pulmonary edema, hyperglycemia, renal loss, fever, phlebitis, thrombosis, blood leakage, injection site pain, uremia

Store this medication in a sealed container to prevent air and moisture from entering, and it is recommended to keep it at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness for a longer period.

Appearance

A colorless, transparent injection solution filled in a translucent high-density polyethylene container, packaged externally.

Package unit

500, 1000 milliliters